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Articles 1 - 6 of 6
Full-Text Articles in Rehabilitation and Therapy
Physical Activity And Exercise With Blood Flow Restriction As Medicine During The Covid-19 Pandemic And Beyond, Isaac J. Wedig
Physical Activity And Exercise With Blood Flow Restriction As Medicine During The Covid-19 Pandemic And Beyond, Isaac J. Wedig
Dissertations, Master's Theses and Master's Reports
During the COVID-19 pandemic, physical activity levels have decreased and sitting time has increased. This is a major concern as physical inactivity increases the risk for severe COVID-19 outcomes. Evidence also indicates that COVID-19 survivors can experience reduced physical function (i.e., ability to complete daily living activities) long after acute illness. Currently, there are no evidence-based guidelines for recovering physical function following COVID-19 infection. Exercise with blood flow restriction (BFR) presents a promising rehabilitation strategy as the benefits of traditional exercise can be achieved using lower intensities. However, several barriers such as cost, access to equipment, and lack of standardized …
System For Powered Ankle-Foot Prosthesis With Active Control Of Dorsiflexion-Plantarflexion And Inversion-Eversion, Mo Rastgaar, Evandro Ficanha, Kenton Kaufman
System For Powered Ankle-Foot Prosthesis With Active Control Of Dorsiflexion-Plantarflexion And Inversion-Eversion, Mo Rastgaar, Evandro Ficanha, Kenton Kaufman
Michigan Tech Patents
A system and method for operating a prosthesis is provided. The system includes a socket configured to engage a residual limb of a subject and a shaft having a first end connected to the socket and an opposing second end. The system also includes a foot piece connected to the second end of the shaft. The foot piece includes an ankle plate and a sole piece configured to contact a surface. The system also includes at least one computer configured to detect a state of the foot piece and to transmit an indication of the state of the foot. The …
Long-Term High Salt Intake Involves Reduced Sk Currents And Increased Excitability Of Pvn Neurons With Projections To The Rostral Ventrolateral Medulla In Rats, Andrew D. Chapp, Renjun Wang, Zixi Cheng, Zhiying Shan, Qing-Hui Chen
Long-Term High Salt Intake Involves Reduced Sk Currents And Increased Excitability Of Pvn Neurons With Projections To The Rostral Ventrolateral Medulla In Rats, Andrew D. Chapp, Renjun Wang, Zixi Cheng, Zhiying Shan, Qing-Hui Chen
Department of Kinesiology and Integrative Physiology Publications
Evidence indicates that high salt (HS) intake activates presympathetic paraventricular nucleus (PVN) neurons, which contributes to sympathoexcitation of salt-sensitive hypertension. The present study determined whether 5 weeks of HS (2% NaCl) intake alters the small conductance Ca2+-activated potassium channel (SK) current in presympathetic PVN neurons and whether this change affects the neuronal excitability. In whole-cell voltage-clamp recordings, HS-treated rats had significantly decreased SK currents compared to rats with normal salt (NS, 0.4% NaCl) intake in PVN neurons. The sensitivity of PVN neuronal excitability in response to current injections was greater in HS group compared to NS controls. The …
High Salt Intake Augments Excitability Of Pvn Neurons In Rats: Role Of The Endoplasmic Reticulum Ca2+ Store, Robert A. Larsen, Andrew D. Chapp, Le Gui, Michael J. Huber, Zixi Jack Cheng, Zhiying Shan, Qing-Hui Chen
High Salt Intake Augments Excitability Of Pvn Neurons In Rats: Role Of The Endoplasmic Reticulum Ca2+ Store, Robert A. Larsen, Andrew D. Chapp, Le Gui, Michael J. Huber, Zixi Jack Cheng, Zhiying Shan, Qing-Hui Chen
Department of Kinesiology and Integrative Physiology Publications
High salt (HS) intake sensitizes central autonomic circuitry leading to sympathoexcitation. However, its underlying mechanisms are not fully understood. We hypothesized that inhibition of PVN endoplasmic reticulum (ER) Ca2+ store function would augment PVN neuronal excitability and sympathetic nerve activity (SNA). We further hypothesized that a 2% (NaCl) HS diet for 5 weeks would reduce ER Ca2+ store function and increase excitability of PVN neurons with axon projections to the rostral ventrolateral medulla (PVN-RVLM) identified by retrograde label. PVN microinjection of the ER Ca2+ ATPase inhibitor thapsigargin (TG) increased SNA and mean arterial pressure (MAP) in a …
Exercise As A Form Of Medicine, Steven J. Elmer
Exercise As A Form Of Medicine, Steven J. Elmer
TechTalks
My research goals are to find better ways to restore musculoskeletal function, maintain health, and improve mobility in healthy and clinical populations. Students in my laboratory (engineering, kinesiology, physical therapy) investigate how humans move and implement new exercise interventions to improve physical conditioning and performance. We work with populations ranging from individuals living with a spinal cord injury to adults recovering from ACL surgery to elite athletes. Applications for our research range from basic aspects of muscle contraction to applied human performance in a variety of settings including rehabilitation, ergonomics, and sport.
Direct Pro-Inflammatory Effects Of Prorenin On Microglia, Peng Shi, Justin L. Grobe, Fiona A. Desland, Guannan Zhou, Xiao Z. Shen, Zhiying Shan, Et. Al.
Direct Pro-Inflammatory Effects Of Prorenin On Microglia, Peng Shi, Justin L. Grobe, Fiona A. Desland, Guannan Zhou, Xiao Z. Shen, Zhiying Shan, Et. Al.
Department of Kinesiology and Integrative Physiology Publications
Neuroinflammation has been implicated in hypertension, and microglia have been proposed to play an important role in the progression of this disease. Here, we have studied whether microglia are activated within cardiovascular regulatory area(s) of the brain during hypertension, especially in high blood pressure that is associated with chronic activation of the renin-angiotensin-system. In addition, we determined whether prorenin, an essential component of the renin-angiotensin-system, exerts direct pro-inflammatory effects on these microglia. Our data indicate that two rodent models which display neurogenic hypertension and over activation of the renin-angiotensin-system in the brain (sRA mice and spontaneously hypertensive rats) exhibit microglial …