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Articles 1 - 14 of 14
Full-Text Articles in Epidemiology
Pufa And Vitamin D And Type 2 Diabetes Inflammatory Markers, Paulo A. Lotufo
Pufa And Vitamin D And Type 2 Diabetes Inflammatory Markers, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
A Stepwise Approach To Stroke Surveillance In Brazil: The Emma (Estudo De Mortalidade E Morbidade Do Acidente Vascular Cerebral) Study, Paulo A. Lotufo
A Stepwise Approach To Stroke Surveillance In Brazil: The Emma (Estudo De Mortalidade E Morbidade Do Acidente Vascular Cerebral) Study, Paulo A. Lotufo
Paulo A Lotufo
Background: Stroke mortality rates in Brazil are the highest in the Americas. Deaths from cerebrovascular disease surpass coronary heart disease. Aim: To verify stroke mortality rates and morbidity in an area of Sa˜o Paulo, Brazil, using the World Health Organization Stepwise Approach to Stroke Surveillance. Methods: We used the World Health Organization Stepwise Approach to Stroke Surveillance structure of stroke surveillance. The hospital-based data comprised fatal and nonfatal stroke (Step 1). We gathered stroke-related mortality data in the community using World Health Organization questionnaires (Step 2). The questionnaire determining stroke prevalence was activated door to door in a family-healthprogramme neighbourhood …
Qualidade De Vida De Estudantes De Enfermagem De Uma Faculdade Privada / Quality Of Life Of Undergraduate Nursing Students From A Private University, Everton Fernando Alves
Qualidade De Vida De Estudantes De Enfermagem De Uma Faculdade Privada / Quality Of Life Of Undergraduate Nursing Students From A Private University, Everton Fernando Alves
Everton Fernando Alves
O presente estudo teve como objetivo avaliar a qualidade de vida dos estudantes no curso de Enfermagem de uma faculdade privada. Realizou-se um estudo descritivo, com abordagem quantitativa, utilizando a Escala de Qualidade de Vida de Flanagan e um instrumento de coleta de dados complementares, contendo questões estruturadas. Resultou numa amostra de 192 (cento e noventa e dois) estudantes. O diagnóstico evidenciou que a maioria dos estudantes está „Satisfeitos‟ e „Pouco satisfeitos‟ com a sua qualidade de vida, entretanto identificou a presença de vários problemas que necessitam de atenção dos educadores. Concluiu-se que se faz necessária a formação de um …
Validation Of A Stroke Symptom Questionnaire For Epidemiological Surveys., Paulo A. Lotufo
Validation Of A Stroke Symptom Questionnaire For Epidemiological Surveys., Paulo A. Lotufo
Paulo A Lotufo
CONTEXT AND OBJECTIVE:Stroke is a relevant issue within public health and requires epidemiological surveillance tools. The aim here was to validate a questionnaire for evaluating individuals with stroke symptoms in the Stroke Morbidity and Mortality Study (Estudo de Mortalidade e Morbidade do Acidente Vascular Cerebral, EMMA), São Paulo, Brazil.DESIGN AND SETTING:This was a cross-sectional study performed among a sample of the inhabitants of Butantã, an area in the western zone of the city of São Paulo.METHODS:For all households in the coverage area of a primary healthcare unit, household members over the age of 35 years answered a stroke symptom questionnaire …
Plasma Prekallikrein Levels Are Positively Associated With Circulating Lipid Levels And The Metabolic Syndrome In Children., James A. Mackenzie, Kristen A. Roosa, Brooks B. Gump, Amy K. Dumas, Kestutis G. Bendinskas
Plasma Prekallikrein Levels Are Positively Associated With Circulating Lipid Levels And The Metabolic Syndrome In Children., James A. Mackenzie, Kristen A. Roosa, Brooks B. Gump, Amy K. Dumas, Kestutis G. Bendinskas
Brooks B. Gump
Plasma prekallikrein (PK) has been shown to be associated with cardiovascular disease (CVD) and its risk factors, but these associations have not been investigated in children. The present study examined PK activity in relation to well-established cardiovascular risk factors in a cohort of children aged 9–11 years (N = 97). We found a significant and positive association between PK and fasting levels of total cholesterol (p < 0.01), non-high-density lipoprotein cholesterol (p < 0.01), and triglycerides (p < 0.001). In addition, there was a significant association between PK activity and the metabolic syndrome, a clustering of risk factors considered to have an impact on atherosclerosis and CVD mortality. Finally, we found that children with a family history of CVD had significantly elevated PK activity. These novel findings warrant further investigations into the relationship between circulating PK levels and CVD risk factors because PK may be involved in the progression of the disease state. Il est bien connu que la pre´kallicre´ine (PK) est associe´e a` la maladie cardiovasculaire (CVD) et a` ses facteurs de risque, mais ces associations n’ont pas e´te´ ve´rifie´es chez les enfants. Cette e´tude se propose de ve´rifier l’association entre l’activite´ de la PK et les facteurs de risque de CVD aupre`s d’une cohorte d’enfants aˆge´s de 9 a` 11 ans (N = 97). On observe une corre´lation positive significative entre la PK et les variables suivantes : la concentration totale de choleste´rol a` jeun (p < 0,01), les concentrations des lipoprote´ines non a` haute densite´ (p < 0,01) et la concentration des triglyce´rides (p < 0,001). De plus, on observe une corre´lation significative entre l’activite´ de la PK et le syndrome me´tabolique constitue par un ensemble de facteurs ayant un effet sur l’athe´roscle´rose et la mortalite´ due a` la CVD. En dernier lieu, les enfants avec des ante´ce´dents familiaux de CVD pre´sentent une plus importante activite´ de la PK, et ce, de fac¸on significative. Ces premie`res observations sugge`rent d’autres e´tudes sur la relation entre la concentration sanguine de PK et les facteurs de risque de CVD, car la PK pourrait eˆtre implique´e dans la progression de la maladi
Socioeconomic Status And Coronary Heart Disease Mortality In The City Of Sao Paulo, Brazil (1996 To 2007), Paulo A. Lotufo
Socioeconomic Status And Coronary Heart Disease Mortality In The City Of Sao Paulo, Brazil (1996 To 2007), Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Non-Inferiority Trials [In Portuguese], Paulo A. Lotufo
Non-Inferiority Trials [In Portuguese], Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Cardiovascular And Cancer Mortality In Brazil, Paulo A. Lotufo
Cardiovascular And Cancer Mortality In Brazil, Paulo A. Lotufo
Paulo A Lotufo
Cancer are not surpassing Cardiovascular Diseases. Here you have an evaluation of mortality in Brazil. The debate was ignited by paper from IARC (International Agency for Research on Cancer) that forecasts cancer deaths surpassing heart diseases rates during de 2020’s. There is no dispute about the fact that - at least in the US and other countries - the decline of mortality deaths for heart diseases presenting a faster pace compared to cancer death rates. It is an epidemiological evidence that must be analyzed and some headline fueling hype as “heart diseases as an old agenda of public health and …
Effects Of Leas And Mecury On The Blood Proteome Of Children, Robert E. Birsall, Michael P. Kiley, Zaneer M. Segu, Christopher D. Palmer, Milan Madera, Brooks B. Gump
Effects Of Leas And Mecury On The Blood Proteome Of Children, Robert E. Birsall, Michael P. Kiley, Zaneer M. Segu, Christopher D. Palmer, Milan Madera, Brooks B. Gump
Brooks B. Gump
Heavy metal exposure in children has been associated with a variety of physiological and neurological problems. The goal of this study was to utilize proteomics to enhance the understanding of biochemical interactions responsible for the health problems related to lead and mercury exposure at concentrations well below CDC guidelines. Blood plasma and serum samples from 34 children were depleted of their most abundant proteins using antibody-based affinity columns and analyzed using two different methods, LC-MS/MS and 2-D electrophoresis coupled with MALDI-TOF/MS and tandem mass spectrometry. Apolipoprotein E demonstrated an inverse significant association with lead concentrations (average being one microgram/deciliter) as …
Gender Differences Of Case-Fatality Rate In A Brazilian Stroke Registry, Paulo A. Lotufo
Gender Differences Of Case-Fatality Rate In A Brazilian Stroke Registry, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Characteristics Of Small Areas With A Higher Stroke Mortality, Paulo A. Lotufo
Characteristics Of Small Areas With A Higher Stroke Mortality, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Higher Frequency Of Stroke Deaths On Monday And Saturday, Paulo A. Lotufo
Higher Frequency Of Stroke Deaths On Monday And Saturday, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Social Inequalities And The Decline Of Stroke Mortality In The City Of Sao Paulo, Brazil, Paulo A. Lotufo
Social Inequalities And The Decline Of Stroke Mortality In The City Of Sao Paulo, Brazil, Paulo A. Lotufo
Paulo A Lotufo
No abstract provided.
Subclinical Hyperthyroidism And Dementia: The Sao Paulo Ageing & Health Study (Spah), Paulo A. Lotufo
Subclinical Hyperthyroidism And Dementia: The Sao Paulo Ageing & Health Study (Spah), Paulo A. Lotufo
Paulo A Lotufo
Background: Several epidemiologic studies have shown a possible association between thyroid function and cognitive decline. Our aim was to evaluate the association of subclinical hyperthyroidism and dementia in a population sample of older people. Methods: A cross-sectional study - São Paulo Ageing & Health Study (SPAH) - in a population sample of low-income elderly people ≥ 65 years-old to evaluate presence of subclinical thyroid disease as a risk factor for dementia. Thyroid function was assessed using thyrotropic hormone and free-thyroxine as well as routine use of thyroid hormones or antithyroid medications. Cases of dementia were assessed using a harmonized one-phase …