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Full-Text Articles in Epidemiology
The Effects Of Maternal Folate On Fetal Brain And Body Size Among Smoking Mothers, Korede K. Adegoke
The Effects Of Maternal Folate On Fetal Brain And Body Size Among Smoking Mothers, Korede K. Adegoke
USF Tampa Graduate Theses and Dissertations
The adverse effects of maternal smoking on infant mortality and morbidity has been well documented in the literature. Maternal tobacco use is causally associated with fetal growth restriction and correlates negatively with folate intake and metabolism. Studies have examined the association between smoking and folate levels during pregnancy, but very few have assessed this relationship using objective and accurate measures of both variables. Furthermore, despite evidence of a causal association between smoking in pregnancy and intrauterine growth restriction, and a plausible relationship between tobacco use and low maternal folate which is required for optimal fetal growth, no experimental study has …
Dna Methylation And Its Association With Prenatal Exposures And Pregnancy Outcomes, Jennifer Straughen
Dna Methylation And Its Association With Prenatal Exposures And Pregnancy Outcomes, Jennifer Straughen
USF Tampa Graduate Theses and Dissertations
Altered DNA methylation may lead to suboptimal fetal programming, increasing the risk of adverse pregnancy outcomes such as small for gestational age (SGA); however, few studies have examined the associations between DNA methylation, prenatal exposures, and fetal outcomes. Cross-sectional data from a larger, ongoing study were used to assess the impact of prenatal smoking on gene specific methylation of umbilical cord blood derived DNA and to investigate the association between gene-specific methylation and risk of SGA. The association between gene-specific DNA methylation and birthweight was also assessed. Maternal and infant covariates were abstracted from medical records, cigarette smoke exposure was …