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Full-Text Articles in Environmental Public Health
Temporal Trends In Phthalate Exposures: Findings From The National Health And Nutrition Examination Survey, 2001-2010, Ami R. Zota, Antonia M. Calafat, Tracey J. Woodruff
Temporal Trends In Phthalate Exposures: Findings From The National Health And Nutrition Examination Survey, 2001-2010, Ami R. Zota, Antonia M. Calafat, Tracey J. Woodruff
Environmental and Occupational Health Faculty Publications
Background: Phthalates are ubiquitous environmental contaminants. Because of potential adverse effects on human health, butylbenzyl phthalate [BBzP; metabolite, monobenzyl phthalate (MBzP)], di-n-butyl phthalate [DnBP; metabolite, mono-n-butyl phthalate (MnBP)], and di(2-ethylhexyl) phthalate (DEHP) are being replaced by substitutes including other phthalates; however, little is known about consequent trends in population-level exposures.
Objective: We examined temporal trends in urinary concentrations of phthalate metabolites in the general U.S. population and whether trends vary by sociodemographic characteristics.
Methods: We combined data on 11 phthalate metabolites for 11,071 participants from five cycles of the National Health and Nutrition Examination Survey (2001–2010). …
Environmental Exposure To Polychlorinated Biphenyls And P,P'-Dde And Sperm Sex-Chromosome Disomy, Megan E. Mcauliffe, Paige L. Williams, Susan A. Korrick, Larisa M. Altshul, Melissa J. Perry
Environmental Exposure To Polychlorinated Biphenyls And P,P'-Dde And Sperm Sex-Chromosome Disomy, Megan E. Mcauliffe, Paige L. Williams, Susan A. Korrick, Larisa M. Altshul, Melissa J. Perry
Environmental and Occupational Health Faculty Publications
Background: Chromosomal abnormalities contribute substantially to reproductive problems, but the role of environmental risk factors has received little attention.
Objectives: We evaluated the association of polychlorinated biphenyl (PCB) and dichlorodiphenyldichloroethylene (p,p´-DDE) exposures with sperm sex-chromosome disomy.
Methods: We conducted a cross-sectional study of 192 men from subfertile couples. We used multiprobe fluorescence in situ hybridization (FISH) for chromosomes X, Y, and 18 to determine XX, YY, XY, and total sex-chromosome disomy in sperm nuclei. Serum was analyzed for concentrations of 57 PCB congeners and p,p´-DDE. Poisson regression models were used to calculate incidence rate ratios (IRRs) for …
Association Of Hexachlorobenzene (Hcb), Dichlorodiphenyltrichloroethane (Ddt), And Dichlorodiphenyldichloroethylene (Dde) With In Vitro Fertilization (Ivf) Outcomes., Shruthi Mahalingaiah, Stacey A. Missmer, Arnab Maity, Paige L. Williams, John D. Meeker, Katharine Berry, Shelley Ehrlich,, Melissa J. Perry, Daniel W. Cramer, Russ Hauser
Association Of Hexachlorobenzene (Hcb), Dichlorodiphenyltrichloroethane (Ddt), And Dichlorodiphenyldichloroethylene (Dde) With In Vitro Fertilization (Ivf) Outcomes., Shruthi Mahalingaiah, Stacey A. Missmer, Arnab Maity, Paige L. Williams, John D. Meeker, Katharine Berry, Shelley Ehrlich,, Melissa J. Perry, Daniel W. Cramer, Russ Hauser
Environmental and Occupational Health Faculty Publications
Background: Hexachlorobenzene (HCB), dichlorodiphenyltrichloroethane (DDT), and dichlorodiphenyldichloroethylene (DDE) are persistent chlorinated pesticides with endocrine activity that may adversely affect the early stages of human reproduction.
Objective: Our goal was to determine the association of serum levels of HCB, DDT, and DDE with implantation failure, chemical pregnancy, and spontaneous abortion in women undergoing in vitro fertilization (IVF) from 1994 to 2003.
Methods: Levels of HCB and congeners of DDT and DDE were measured in serum collected during the follicular phase. Multivariable-adjusted statistical models accommodating multiple outcomes and multiple cycles per woman were used to estimate the relation between serum pesticide levels …