Behavior and Behavior Mechanisms Commons^™

Septohippocampal Gabaergic Neurons Mediate The Altered Behaviors Induced By N-Methyl-D-Aspartate Receptor Antagonists., Jingyi Ma, Siew Kian Tai, L Stan Leung

Physiology and Pharmacology Publications

We hypothesize that selective lesion of the septohippocampal GABAergic neurons suppresses the altered behaviors induced by an N-methyl-D-aspartate (NMDA) receptor antagonist, ketamine or MK-801. In addition, we hypothesize that septohippocampal GABAergic neurons generate an atropine-resistant theta rhythm that coexists with an atropine-sensitive theta rhythm in the hippocampus. Infusion of orexin-saporin (ore-SAP) into the medial septal area decreased parvalbumin-immunoreactive (GABAergic) neurons by ~80%, without significantly affecting choline-acetyltransferase-immunoreactive (cholinergic) neurons. The theta rhythm during walking, or the immobility-associated theta induced by pilocarpine, was not different between ore-SAP and sham-lesion rats. Walking theta was, however, more disrupted by atropine sulfate in ore-SAP than …

An Integrative Review Of Out-Patient Teaching For Children With Attention Deficit Hyperactivity Disorder, Elizabeth Hicks, Melissa Hogan, Kendra Parker

Pharmacy and Nursing Student Research and Evidence-Based Medicine Poster Session

Attention deficit hyperactivity disorder is most prevalent in children. Symptoms include inappropriate levels of hyperactivity, impulsive behavior, and lack of attention. 3-9% of children suffer from the symptoms of ADHD. Treatments of ADHD vary: pharmacological therapy includes stimulants and non-stimulants, whereas non-pharmacological treatments include restriction diet, nutrient supplements, and psychosocial interventions. Psycho-stimulant treatment is not beneficial for 20-30% of children with ADHD. The purpose of this study is to determine if diet/nutrition and parent training treatments are effective in managing the symptoms of children with ADHD.

Accuracy Of Self-Reported Sun Exposure And Sun Protection Behavior, Joel J. Hillhouse, Robert Turrisi, James Jaccard, June K. Robinson

ETSU Faculty Works

The objective of this study was to compare the accuracy of self-reported skin cancer risk outcome measures proposed as standards by prevention experts to aggregated estimates of behavior from weekly diaries. Weekly electronic diaries of ultraviolet radiation (UVR) behaviors, initially validated by comparison with daily electronic diaries, were used to assess the accuracy of commonly used end-of-summer self-reported measures among 250 adults. Results revealed low biases, and good correspondence between simple open-ended self-reported estimates of days outside, hours outside, sunbathing days and hours, and days outside when not protected by either sunscreen, long-sleeved shirts, hats, or shade. Rating scale measures …

Parametric Studies Of Antipsychotic-Induced Sensitization In The Conditioned Avoidance Response Model: Roles Of Number Of Drug Exposure, Drug Dose, And Test–Retest Interval, Natashia Swalve, Ming Li

Department of Psychology: Faculty Publications

Repeated haloperidol and olanzapine treatment produces an enhanced disruption of avoidance responding, a validated measure of antipsychotic activity. Experimental parameters affecting this sensitization-like effect have not been thoroughly examined. The present study investigated the role of three parameters (number of injections, dose, and interval between initial exposure and challenge) in antipsychotic sensitization in the conditioned avoidance response paradigm. Well-trained Sprague–Dawley rats received different numbers of drug treatment (1–5 days) or different doses of haloperidol (0.025–0.10 mg/kg, subcutaneously) or olanzapine (0.5–2.0 mg/kg, subcutaneously). After certain time intervals (4, 10 or 17 days), they were tested for the expression of haloperidol or …

Sleep Hygiene And Problem Behaviors In Snoring And Non- Snoring School-Age Children, Lisa A. Witcher, David Gozal, Dennis L. Molfese, Scott M. Salathe, Karen Spruyt, Valerie Mclaughlin Crabtree

Center for Brain, Biology, and Behavior: Faculty and Staff Publications

Objectives—The effects of sleep-disordered breathing, sleep restriction, dyssomnias, and parasomnias on daytime behavior in children have been previously assessed. However, the potential relationship(s) between sleep hygiene and children’s daytime behavior remain to be explored. The primary goal of this study was to investigate the relationship between sleep hygiene and problematic behaviors in non-snoring and habitually snoring children.

Methods—Parents of 100 5- to 8-year-old children who were reported to snore “frequently” to “almost always,” and of 71 age-, gender-, and ethnicity-matched children who were reported to never snore participated in this study. As part of a larger, ongoing study, …

Neurological Soft Signs In Persons With Amnestic Mild Cognitive Impairment And The Relationships To Neuropsychological Functions, Hui-Jie Li, Peng-Yun Wang, Yang Jiang, Raymond C.K. Chan, Hua-Li Wang, Juan Li

Behavioral Science Faculty Publications

BACKGROUND: Neurological abnormalities have been reported in people with amnestic mild cognitive impairment (aMCI). The current study aimed to examine the prevalence of neurological soft signs (NSS) in this clinical group and to examine the relationship of NSS to other neuropsychological performances.

METHODS: Twenty-nine people with aMCI and 28 cognitively healthy elderly people were recruited for the present study. The NSS subscales (motor coordination, sensory integration, and disinhibition) of the Cambridge Neurological Inventory and a set of neuropsychological tests were administered to all the participants.

RESULTS: People with aMCI exhibited significantly more motor coordination signs, disinhibition signs, and total NSS …

The Stress Coping Skills Of Undergraduate Collegiate Aviators, Jennifer Kirschner, John P. Young, Richard Fanjoy, Donald Petrin

Aviation Technology Graduate Student Publications

An important human factors research interest area is error reduction. Although pilots placed in highly stressful situations have an increased chance of making errors, they use coping skills to lower their stress level and reduce the likelihood of errors. Typically, coping skills are conceptually separated into three types: active coping skills change the situation to make it inherently less stressful, emotion-focused coping skills use discussion or thinking about the situation in a different way to diminish the negative emotional reaction associated with the stressful situation, and avoidant coping skills allow one to mentally and/or physically disengage through the use of …

Adjusting For Confounding By Neighborhood Using A Proportional Odds Model And Complex Survey Data, Babette A. Brumback, Amy B. Dailey, Hao W. Zheng

Health Sciences Faculty Publications

In social epidemiology, an individual's neighborhood is considered to be an important determinant of health behaviors, mediators, and outcomes. Consequently, when investigating health disparities, researchers may wish to adjust for confounding by unmeasured neighborhood factors, such as local availability of health facilities or cultural predispositions. With a simple random sample and a binary outcome, a conditional logistic regression analysis that treats individuals within a neighborhood as a matched set is a natural method to use. The authors present a generalization of this method for ordinal outcomes and complex sampling designs. The method is based on a proportional odds model and …

Water Pipe Smoking Amongst The University And College Students Of Karachi, Pakistan, Shehla Batool Jaffri, Aisha Yousuf, Waris Qidwai

Department of Family Medicine

Background:

An extensive literature search revealed that water pipe smoking is an emerging health risk and deserves the attention of health professionals. This study was therefore undertaken to determine the frequency of water pipe smoking among students in college and universities of Pakistan and to assess the practices, knowledge and attitude towards water pipe smoking among them.

Method:

A cross sectional survey was conducted in the College and Universities of Karachi, Pakistan from April 2009 to October 2009. Students were selected through non probability sampling and given self administered questionnaire after the informed consent.

Result:

A total …

Does Emotional Memory Enhancement Assist The Memory-Impaired?, Lucas S. Broster, Lee X. Blonder, Yang Jiang

Behavioral Science Faculty Publications

We review recent work on emotional memory enhancement in older adults and patients with mild cognitive impairment (MCI) or Alzheimer dementia (AD) and evaluate the viability of incorporating emotional components into cognitive rehabilitation for these groups. First, we identify converging evidence regarding the effects of emotional valence on working memory in healthy aging. Second, we introduce work that suggests a more complex role for emotional memory enhancement in aging and identify a model capable of unifying disparate research findings. Third, we survey the neuroimaging literature for evidence of a special role for the amygdala in MCI and early AD in …

Perceived Health In Lung Cancer Patients: The Role Of Positive And Negative Affect, Jameson K. Hirsch, Andrea R. Floyd, Paul R. Duberstein

ETSU Faculty Works

Purpose: To examine the association of affective experience and health-related quality of life in lung cancer patients, we hypothesized that negative affect would be positively, and positive affect would be negatively, associated with perceived health.

Methods: A sample of 133 English-speaking lung cancer patients (33% female; mean age = 63.68 years old, SD = 9.37) completed a battery of self-report surveys.

Results: Results of our secondary analysis indicate that trait negative affect was significantly associated with poor physical and social functioning, greater role limitations due to emotional problems, greater bodily pain, and poor general health. Positive affect was significantly associated …

A Community-Integrated Home Based Depression Intervention For Older African Americans: Descripton Of The Beat The Blues Randomized Trial And Intervention Costs., Laura N Gitlin, Lynn Fields Harris, Megan Mccoy, Nancy L Chernett, Eric Jutkowitz, Laura T Pizzi

Center for Applied Research on Aging and Health Research Papers

ABSTRACT: BACKGROUND: Primary care is the principle setting for depression treatment; yet many older African Americans in the United States fail to report depressive symptoms or receive the recommended standard of care. Older African Americans are at high risk for depression due to elevated rates of chronic illness, disability and socioeconomic distress. There is an urgent need to develop and test new depression treatments that resonate with minority populations that are hard-to-reach and underserved and to evaluate their cost and cost-effectiveness. METHODS/DESIGN: Beat the Blues (BTB) is a single-blind parallel randomized trial to assess efficacy of a non-pharmacological intervention to …

The Effects Of Adolescent Binge Drinking On Corticotropin-Releasing Factor Cells In The Amygdala And Social Predictors Of Alcohol Intake In Male And Female Rats, Chrisanthi Karanikas

Masters Theses 1911 - February 2014

Alcohol is one of the most common drugs of choice among adolescents. Normally, the method of consumption is drinking large quantities of alcohol in short periods of time, otherwise known as “binge drinking.” Corticotropin releasing factor (CRF) stress peptide producing cells in central nucleus of the amygdala (CeA) has been implicated in behavioral responses to stress and addiction. The goals of this thesis were to determine the effects of voluntary binge drinking in adolescence and vapor-induced alcohol dependence in adulthood on CRF cells in the CeA. These studies were done using an operant model of voluntary binge drinking in rodents …

The Impact Of A Naturalistic Stressor On Spontaneous Alternation Behavior: A New Animal Model Of Ocd, Christina Finch

Behavioral Neuroscience Honors Papers

Over the past few decades, various animal models of obsessive compulsive disorder (OCD) have been developed. Similarly, various stressors have been used throughout animal research. The Spontaneous Alternation Behavioral (SAB) model is a well-established model of OCD while 2,5-dihydro-2,4,5-trimethylthiazoline (TMT) has recently become a popular naturalistic stressor. This study linked the two together, thus modeling the effect of stress on OCD behaviors. After living in an enriched or standard environment for 3 weeks, male Sprague-Dawley rats were exposed to either TMT or no odor, and then were examined in the SAB task. Unlike what was hypothesized, the enriched environment proved …

Anthropological Data Regarding The Adaptiveness Of Hebephilia, Raymond B. Hames, Ray Blanchard

Department of Anthropology: Faculty Publications

Hebephilia is the sexual attraction to early pubertal children in Tanner Stages 2 and 3, generally ages 11 through 14.

The second author of this letter (R.B.), a member of the Paraphilias Subworkgroup of the Work Group on Sexual and Gender Identity Disorders for DSM-5, proposed a diagnostic entity for DSM-5 that resembles the ICD-10 model, but with a different name: Pedohebephilic Disorder. In the original proposal (Blanchard, 2010a), this disorder would have three subtypes: pedophilic, hebephilic, and pedohebephilic. In the current version of the proposal, which is still under consideration, the name has been changed to Pedophilic Disorder, in …

Cures For Procrastination In College Students, Ashley-Tate Hollis

A with Honors Projects

This project examines some cures for procrastination in college students.

Differential Effects Of Acute Amphetamine And Phencyclidine Treatment And Withdrawal From Repeated Amphetamine Or Phencyclidine Treatment On Social Interaction And Social Memory In Rats, Ming Li, Wei He, Rebecca Munro

Department of Psychology: Faculty Publications

Although animal models based on amphetamine (AMPH) or phencyclidine (PCP) treatment have been used extensively to study the neurobiological and behavioral characteristics of schizophrenia, there are conflicting reports regarding their validity in modeling the negative symptoms and cognitive deficits of schizophrenia. The present study examined how acute AMPH or PCP treatment (Experiment 1) and withdrawal from repeated AMPH treatment (Experiment 2) or PCP treatment (Experiment 3) affects social behavior and social recognition memory in male Sprague-Dawley rats. Each subject was tested on two consecutive days. On the first day, the rats were tested four times (5 min/each) at 10-min intervals …

A Phenomenological Exploration Of The Childfree Choice In A Sample Of Australian Women, Joanne Doyle, Julie Ann Pooley, Lauren Breen

Research outputs 2012

Choosing not to have children is considered a deviation from cultural norms, particularly the dominant pronatalist discourse; this is especially so for women. However, little research has documented the experience of Australian women who have consciously chosen to remain childless. Ten voluntarily childfree women participated in unstructured interviews about their choice and its ramifications. The data analysis revealed three broad themes – the experiences and processes of making the choice; the ongoing effects of their choice, ranging from support and acceptance to pressure and discrimination; and no regret as the women described engaging in meaningful, generative activities that contributed to …

Crime Prevention: The Role Of Individual Resilience Within The Family, Catherine Ferguson, Craig Harms, Julie Ann Pooley, Lynne Cohen, Stuart Tomlinson

Research outputs 2012

Resilience is context dependent but for resilience to be present, two elements must co-occur: adversity (i.e., high-risk situation/threat) and successful adaptation/competence. An understanding of resilience is important for professionals dealing with at-risk families. This exploratory research investigated how individuals caring for a family member with a mental illness adapted to the role of carer or supporter. Fifteen participants mostly aged 50 years or more were interviewed. Content analysis was used to develop themes from the interview transcripts. Seven themes were elicited from the data. Three of these fit with existing knowledge about challenges faced by offenders’ families. The article concludes …

A Theory Of The Mind As A Complex System, Craig Speelman, Kim Kirsner, Stephan Halloy

Research outputs 2012

Five principles of skill acquisition are presented based on a review of research on human learning and expertise. Essentially these principles state that practice leads to faster and more efficient uses of knowledge. This enables faster performance and results in less demand on mental resources. In turn these outcomes enable higher level behaviours to be attempted. Ultimately skills are developed through refinement of many component processes. A theory of the mind is proposed that borrows from theories of complex adaptive systems. In this theory, the mind is conceived of as consisting of agents that compete for resources associated with processing …

Posttraumatic Stress And Posttraumatic Growth And Their Relationship To Coping And Self-Efficacy In Northwest Australian Cyclone Communities, Julie Ann Pooley, Lynne Cohen, Moira O'Conner, Myra Taylor

Research outputs 2012

The main focus of disaster research conducted to date has been on providing insights into the negative consequences of experiencing a serious threat or adversity. The present study extends this research endeavor by investigating the positive posttrauma resiliency experiences of 512 survey respondents living in four cyclone-prone communities in Northwest Australia. The findings reveal that disaster stress is often accompanied by disaster growth and, thus, provides an alternative resilience-based way of viewing postdisaster interventions.

Cognitive Effects Of One Season Of Head Impacts In A Cohort Of Collegiate Contact Sport Athletes, Thomas W. Mcallister,, Laura A. Flashman, Arthur C. Maerlender, Richard M. Greenwald, Jonathan G. Beckwith, Tor D. Tosteson, Joe Crisco, Per Gunner Brolinson, Stefan Duma, Ann-Christine Duhaime, M. R. Grove, John H. Turco

Center for Brain, Biology, and Behavior: Faculty and Staff Publications

Objective: To determine whether exposure to repetitive head impacts over a single season negatively affects cognitive performance in collegiate contact sport athletes.

Methods: This is a prospective cohort study at 3 Division I National Collegiate Athletic Association athletic programs. Participants were 214 Division I college varsity football and ice hockey players who wore instrumented helmets that recorded the acceleration-time history of the head following impact, and 45 noncontact sport athletes. All athletes were assessed prior to and shortly after the season with a cognitive screening battery (ImPACT) and a subgroup of athletes also were assessed with 7 measures from a …