Behavior and Behavior Mechanisms Commons^™

Effects Of The Selective Gsk3b Inhibitor, Tideglusib, On Ethanol Consumption, Anxiety-Like Behavior, Taste Preference, And Downstream Proteins, Sam Gottlieb, Douglas Bledsoe, Jessica L. Maltman, Alanna Morgan, Jennifer T. Wolstenholme, Michael F. Miles

Graduate Research Posters

Background: We have shown modulations in glycogen synthase kinase 3 beta (GSK3B) abundance or activity regulate ethanol consumption, suggesting potential as a therapeutic target for alcohol use disorder (AUD). Here we report the GSK3B inhibitor tideglusib’s actions on ethanol consumption, basal behaviors, and modulation of GSK3B targets.

Methods: C57BL/6J males and females received i.g. 200mg/kg tideglusib, except drinking-in-the-dark (males;100mg/kg i.p.). Drinking-in-the-dark (DID): Mice given 20% ethanol 4-hours, 4-days/week x 3 weeks and then i.p. tideglusib or vehicle x 4 days in a Latin Square design with ethanol consumption measured daily. Light/Dark Box: Mice gavaged with tideglusib or vehicle …

The Relation Of Seasonal Patterns To Mood Changes And Gender Differences In College-Aged Students, Mariah Meza

Student Research Posters

This study examined college students’ moods during different seasons patterns throughout the year. Previous research has indicated that many individuals feel more lethargic, lonely and moody during the winter months (Rohan & Sigmon, 2000). These mood and behavior patterns clearly depend on specific seasons of the year. However, many studies have produced inconsistent findings and current data on how weather impacts college aged students moods in California (Lucht & Kasper, 1999). There are many inconsistent studies in the United States that indicate whether there is a higher fluctuation in women’s moods during seasonal change than there is with men(Chotai, Smedh, …