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Social and Behavioral Sciences

2020

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Full-Text Articles in Behavior and Behavior Mechanisms

Exploring Accessibility And Social Inclusion For Children With Hearing Impairments In Residential Camps Through The Occupational Therapy Lens, Tiffany Coles Dec 2020

Exploring Accessibility And Social Inclusion For Children With Hearing Impairments In Residential Camps Through The Occupational Therapy Lens, Tiffany Coles

Student Capstone Papers

Children are encouraged to engage in various play, leisure, and social participation activities to enhance the development of life skills, independence, and social skills. A common leisure and social participation activity for children aged 6 to 18-years-old is to attend residential camp. Residential camps provide children a structured opportunity to engage in leisure activities while learning to become independent and self-confident when socializing and making new friends. Attending camp can be a fun and engaging environment to help accelerate growth in key developmental outcomes, such as positive identity, social skills, physical skills, positive values, and spirituality.

Within the residential camp …


Experimental Manipulations To Test Theory-Driven Mechanisms Of Cognitive Behavior Therapy, Matthew W. Southward, Shannon Sauer-Zavala Dec 2020

Experimental Manipulations To Test Theory-Driven Mechanisms Of Cognitive Behavior Therapy, Matthew W. Southward, Shannon Sauer-Zavala

Psychology Faculty Publications

Despite decades of randomized-controlled trials demonstrating the efficacy of cognitive-behavior therapy (CBT), the mechanisms by which CBT achieves its effects remain unclear. Here, we describe how one adaptive intervention, the sequential multiple assignment randomized trial (SMART), can be used to randomize patients at multiple decision points in treatment to draw stronger causal claims about mechanisms unfolding in the course of CBT. We illustrate this design using preliminary data and case examples from an ongoing SMART in which we are testing the role of aversive reactions to negative emotions as a hypothesized mechanism of change in the Unified Protocol. Finally, we …


Pediatric Asthma And Psychological Resilience: Examining Whether Family Functioning And Social Support Relate To Asthma Symptoms And Lung Function, Dalia Jaafar, Natasha H. Hikita, Pornchai Tirakitsoontorn, Azucena Talamantes, Anchalee Yuengsrigul, Eric Sternlicht, Brooke N. Jenkins Dec 2020

Pediatric Asthma And Psychological Resilience: Examining Whether Family Functioning And Social Support Relate To Asthma Symptoms And Lung Function, Dalia Jaafar, Natasha H. Hikita, Pornchai Tirakitsoontorn, Azucena Talamantes, Anchalee Yuengsrigul, Eric Sternlicht, Brooke N. Jenkins

Student Scholar Symposium Abstracts and Posters

Upwards of 6 million children in the United States are afflicted with pediatric asthma. While previous research has linked asthma to multiple contributing biological and environmental factors, recent research suggests that psychological and social factors may have an impact on physiological outcomes of asthma like lung function and lung inflammation. Therefore, we suggest the need to study the impact of positive psychological factors such as a well-functioning family environment and beneficial social support on symptoms and lung function of children diagnosed with asthma. In the present pilot study, we recruited a total of 15 children with a confirmed asthma diagnosis …


Smart Homes For Smart Health: Developing An Interactive System To Reduce In-Home Secondhand Smoke, Christie Kika, Janice Han, Vincent Berardi Dec 2020

Smart Homes For Smart Health: Developing An Interactive System To Reduce In-Home Secondhand Smoke, Christie Kika, Janice Han, Vincent Berardi

Student Scholar Symposium Abstracts and Posters

Smoke from any source is potentially harmful because it contains fine particulate matter that is associated with acute and chronic conditions. Second-hand smoke (SHS) is particularly unsafe for children due to biological characteristics (higher breathing rates, immature lungs and underdeveloped immune systems) that make it difficult to filter toxins.To address this concern, we recently completed Project Fresh Air (PFA), an NIH-funded R01 intervention that installed air particle sensors in the households of tobacco smokers who lived with children. The purpose of our research is to investigate and develop efficient smart home devices that monitor SHS in various living spaces to …


Historical Trauma Response Scores As A Function Of Unresolved Grief And Substance Use Disorder In American Indian Populations, Andrew R. Saunders Nov 2020

Historical Trauma Response Scores As A Function Of Unresolved Grief And Substance Use Disorder In American Indian Populations, Andrew R. Saunders

Undergraduate Research Symposium

Abstract

Researchers are interested in the outcomes of interventions, specifically, measuring historical trauma (HT) among American Indian/Alaska Native communities and the long-term distress and substance abuse as a result of historical trauma response (HTR). Previous literature has implicated limitations in the clinical conceptualization of the relationship between intergenerational transfer of HTR and substance abuse. The aim of the current study is to examine treatment efficacy of 50 homosexual, American Indian males randomized to a culturally-adapted juxtaposition of (1) Group Interpersonal Psychotherapy (IPT), (2) Cognitive Processing Therapy (CPT), and (3) Historical Trauma and Unresolved Grief Intervention (HTUG), or (4) waitlisted on …


Sexually Dimorphic Oxytocin Receptor-Expressing Neurons In The Anteroventral Periventricular Nucleus Regulates Maternal Behavior, Kaustubh Sharma Nov 2020

Sexually Dimorphic Oxytocin Receptor-Expressing Neurons In The Anteroventral Periventricular Nucleus Regulates Maternal Behavior, Kaustubh Sharma

LSU Doctoral Dissertations

The neurohypophysial hormone oxytocin is involved in the regulation of social behaviors, including social recognition, pair bonding, and sex-specific parental behaviors in a variety of species. Oxytocin triggers these social behaviors by binding to oxytocin receptors (OXTR) in various parts of the brain. Oxytocin-induced sex-typical behavior, therefore, suggests a sexual dimorphic distribution of OXTR in the brain. In recent years, the oxytocin system in the brain received tremendous attention as a potential pharmacological target for treatment of many psychiatric disorders, such as anxiety, autism spectrum disorders, and even sex-specific psychiatric disorder like postpartum depression (PPD). An important problem and a …


Aerobic Exercise With Superimposed Virtual Reality Improves Cognitive Flexibility And Selective Attention In Young Males, Borja Sañudo, Ellie Abdo, Mario Bernardo-Filho, Redha Taiar Nov 2020

Aerobic Exercise With Superimposed Virtual Reality Improves Cognitive Flexibility And Selective Attention In Young Males, Borja Sañudo, Ellie Abdo, Mario Bernardo-Filho, Redha Taiar

Publications

The literature to date is limited regarding the implantation of VR in healthy young individuals with a focus on cognitive function. Thirty healthy males aged between 22.8 and 24.3 years volunteered to participate in the study randomly and were assigned to one of two groups with alike exercises: an experimental group (GE, n = 15) that performed an exercise protocol with a VR game and a controlled group that performed the exercise protocol without the VR (CON, n = 15). A 128-card computerized version of the Wisconsin Card Sorting Task (WCST) and the Stroop test were completed before and after …


Determining The Effectiveness Of A Peer Support Person In Individuals With Depression Symptoms, Donna K. Reeves Nov 2020

Determining The Effectiveness Of A Peer Support Person In Individuals With Depression Symptoms, Donna K. Reeves

Electronic Theses and Dissertations

Abstract

This study’s aim was to evaluate the effectiveness of an existing peer support program as an adjunct treatment for patients with depression. This retrospective evaluation analyzed the total scores of 110 patients with depression on the PHQ-9 questionnaire at the initial assessment (Time 1), at 6-weeks (Time 2), and then at 12-weeks (Time 3). The participants were divided into two groups, those who enrolled in a peer support program (n = 55) and those without peer support (n = 55). PHQ-9 total scores for each time interval were compared for the two groups utilizing independent sample t-tests …


The Impact Of Levodopa Administration On Learning From Short-Term And Long-Term Action Consequences: A Paradigm Validation., Masood Rezaei Oct 2020

The Impact Of Levodopa Administration On Learning From Short-Term And Long-Term Action Consequences: A Paradigm Validation., Masood Rezaei

Electronic Thesis and Dissertation Repository

Behavioral and neuroimaging studies have identified two valuation systems in the human brain for controlling behavior known as model-free (MF) and model-based (MB). MF is based on immediate evaluation and MB is based on long-term evaluation of the outcome of our decisions. Previous studies suggest that dopamine baseline activity may play an important role in the balance between the two systems and determine how they compete or interact in controlling our actions. The overarching aims of this study is to investigate the impact of levodopa administration on learning from immediate and long-term action consequences, and to dissociate the role of …


Empowering Nurses Of Minority In The Face Of Incivility And Bullying: Through The Lens Of Phenomenology, Corrine Floyd Oct 2020

Empowering Nurses Of Minority In The Face Of Incivility And Bullying: Through The Lens Of Phenomenology, Corrine Floyd

Dissertations

Abstract

Up to 85% of nurses have reported exposure to incivility in the workplace (Hunt & Marini, 2012). The often-subtle nature of incivility toward nurses in a minority population may partially explain why it remains a problem. Healthcare organizations realize the need for civility to counter the high turnover rate, staff shortages, and low job satisfaction reported by nurses, but lack understanding of how nurses of a minority population perceive incivility and bullying. This study aimed to answer the research question how do nurses with minority representation experience incivility and bullying versus empowerment in the workplace? A descriptive phenomenological design …


We All Feel Feelings, Ben Ohene Aug 2020

We All Feel Feelings, Ben Ohene

Theses and Dissertations

Consisting of three illustrated books, We All Feel Feelings is designed as a vehicle for the discussion of emotional and mental health with young boys. These books will help foster a mindset of openness and acceptance through different methods of displaying and understanding emotions.


Treatment-Associated Improvements In Self-Regulation And Mood As Theory-Based Correlates Of Increased Self-Efficacy For Weight-Management Behaviors, James J. Annesi Jun 2020

Treatment-Associated Improvements In Self-Regulation And Mood As Theory-Based Correlates Of Increased Self-Efficacy For Weight-Management Behaviors, James J. Annesi

Health Behavior Research

Expanded understanding of the psychosocial dynamics of weight-loss treatment processes is required to improve consistently poor results. Women with obesity of ages 40–59 years participated in self-regulation-based (n = 41) and information-based (n = 46) treatments. Improvements in self-regulation and self-efficacy related to exercise and eating, mood, exercise, intake of fruits/vegetables and sweets, and weight were significant, and generally greater in the self-regulation group. Exercise- and eating-behavior changes significantly mediated the prediction of self-efficacy changes by changes in self-regulation, with mood change significantly adding to the prediction strength. Findings suggested the value in supporting exercise for its psychosocial …


A Case For Delirium Risk Prediction Models To Aid In Triaging Resources To Those Most At Risk An Integrative Literature Review, Tammy Perttula Jun 2020

A Case For Delirium Risk Prediction Models To Aid In Triaging Resources To Those Most At Risk An Integrative Literature Review, Tammy Perttula

Nursing Masters Papers

Abstract

Delirium is a complex syndrome resulting from compounding effects of acute illness, comorbidities, and the environment. It results in adverse outcomes: elevated mortality rates, length of stay, readmissions, institutionalization, long-term cognitive changes, and diminished quality of life. The rate of iatrogenic delirium is astounding, ranging from 10%-89%. There are no curative treatments; thus, primary prevention is the key. The purpose of this literature review is to identify and critique the research for the accuracy of risk stratification and feasibility in practice. Support for interventions that prevent delirium is mounting; however, interventions are resource-intensive and often not implemented. Researchers have …


Sense Of Purpose In Life And Five Health Behaviors In Older Adults, Eric S. Kim, Koichiro Shiba, Julia K. Boehm, Laura D. Kubzansky Jun 2020

Sense Of Purpose In Life And Five Health Behaviors In Older Adults, Eric S. Kim, Koichiro Shiba, Julia K. Boehm, Laura D. Kubzansky

Psychology Faculty Articles and Research

Accumulating evidence shows that a higher sense of purpose in life is associated with lower risk of chronic conditions and premature mortality. Health behaviors might partially explain these findings, however, the prospective association between sense of purpose and health behaviors is understudied. We tested whether a higher sense of purpose at baseline was associated with lower likelihood of developing unhealthy behaviors over time. Prospective data were from the Health and Retirement Study, a national sample of U.S. older adults. Our sample included 13,770 adults assessed up to five times across eight years. Among people who met recommended guidelines for a …


Scope Of Attention Variation As A Function Of Anxiety And Depression, Kathleen O'Donnell Jun 2020

Scope Of Attention Variation As A Function Of Anxiety And Depression, Kathleen O'Donnell

Electronic Theses, Projects, and Dissertations

As a social species, correct emotional perception is so vital, that the human brain has evolved a mechanism to control attentional choices by exerting a narrowed field of perception during danger, called the scope of attention (SoA). The SoA determines what information will be focused on or ignored by blocking the perception of non-relevant items and increasing selective focus on danger; even if danger is merely a sad-face. The emotional items blocked from perception cannot be remembered because they were never perceived. But, attention-control to emotional stimuli also varies with mood, as seen in mood-disorders. A mood-disorder’s effect upon the …


Mental Health Challenges Among Ethnic Minorities College Students, Fiorella G. Valles, Ruben Gonzalez Jun 2020

Mental Health Challenges Among Ethnic Minorities College Students, Fiorella G. Valles, Ruben Gonzalez

Electronic Theses, Projects, and Dissertations

This research study explored the challenges of mental health-seeking services of college students of color in the San Bernardino area. College students of different ethnicities have unique needs and challenges that contrast with the general student population. Previous research stated that students of color deal with a greater number of unmet mental health needs and indicates a connection between mental health and attaining a college degree (Arria et al., 2013). To increase the utilization of mental health amongst students of color, this study aimed to identify the influencing factors that prevented students from help-seeking. The research design of this research …


Mental Associations And Music Therapy: Including The History Of Associationism And The Neurology Of Associations, Dianna Rose May 2020

Mental Associations And Music Therapy: Including The History Of Associationism And The Neurology Of Associations, Dianna Rose

Expressive Therapies Capstone Theses

Associations are formed in our minds based upon three elements: sensory experience, emotions, and memories. These associations, unique to each individual, dictate thoughts, beliefs, behaviors, and actions. Some are necessary and supportive, while others can be maladaptive. Established associations can be changed, and new associations can be formed, to align with a client’s goals. The literature presents a strong history of associationism, as well as a body of research that demonstrates the neurological processes of how mental associations are formed. There are also studies showing how music activates the brain. However, there is a lack of research which draws direct …


Calling Out The Trolls: Responses To Witnessing Use Of The “Troll” Label As A Defense In An Online Group Context, Dene E. M. Wamsley May 2020

Calling Out The Trolls: Responses To Witnessing Use Of The “Troll” Label As A Defense In An Online Group Context, Dene E. M. Wamsley

Graduate Theses and Dissertations

Although the term “troll” has existed since the 1980s, its meaning has shifted in recent years as social media use has increased. People provide contrasting and imprecise definitions for what constitutes “trolling,” and often apply the term subjectively to describe online discussants who are uncivil, who are deviant, and who and present counter-attitudinal opinions. Exposure to deviance, counter-attitudinal information, and incivility often leads to unwanted psychological effects. In theory, labeling an uncivil, counter-attitudinal deviant as a “troll” proposes that their intention is to disrupt the conversation and upset other discussants, which provides a reason for why incivility is used, and …


An Experimental Test Of The Effects Of Sleep Deprivation On Approach Behavior, Rebecca L. Campbell May 2020

An Experimental Test Of The Effects Of Sleep Deprivation On Approach Behavior, Rebecca L. Campbell

Graduate Theses and Dissertations

Emotion regulation and sleep have been identified as mechanisms that may be involved in the development and maintenance of many mental health disorders. However, there has been little research into the relation between sleep and emotion regulation. To address this gap in knowledge, a novel study was conducted. We hypothesized that sleep deprived individuals would demonstrate less approach behavior toward a negatively valenced stimulus, as well as increased self-reported avoidance, compared to a control group. To test this, a randomized controlled experiment using a behavioral measure of approach and a self-report measure of avoidance was conducted. Fifty-two healthy individuals ages …


The Impact Of Stress On Diet, Sleep, And Exercise Amongst College Students, Jessica Rizzo May 2020

The Impact Of Stress On Diet, Sleep, And Exercise Amongst College Students, Jessica Rizzo

Senior Honors Projects

Stress is something that everyone faces in their lifetime and has an everlasting impact on their health. College students face high levels of stress throughout the semester, but how is that impacting their behavior? I conducted a survey alongside Dr. Melanson, a professor in the Department of Nutrition and Food Sciences, to see just how college students are reacting to stress. The survey was circulated to different departments and classes to achieve a widespread collection of data. The survey remained completely anonymous and posed questions about eating, exercise, and sleep habits, along with questions on demographics and stress levels. Our …


Physical Inactivity: A Behavioral Disorder In The Physical Therapist’S Scope Of Practice, Matthieu P. Boisgontier, Maura D. Iversen May 2020

Physical Inactivity: A Behavioral Disorder In The Physical Therapist’S Scope Of Practice, Matthieu P. Boisgontier, Maura D. Iversen

SHU Faculty Publications

In health, the gold standard is a state of complete physical, mental, and social well-being.This state is weakened by physical inactivity, which involves a higher risk of cardiovascular disease, hypertension, diabetes, cancer, depression, and obesity. Moreover, 6% to 10% of all deaths from non-communicable diseases worldwide can be attributed to physical inactivity. These adverse effects of physical activity provide evidence that physically active individuals are closer to the gold standard of health than inactive individuals. Therefore, physical activity – not inactivity – should be the standard reference behavior. In this framework, physical inactivity is a clinically significant disturbance in an …


The Role Of Dopamine In Decision Making Processes In Drosophila Melanogaster, Michelle C. Bowers May 2020

The Role Of Dopamine In Decision Making Processes In Drosophila Melanogaster, Michelle C. Bowers

Undergraduate Honors Theses

Understanding the neural processes that mediate decision making is a relatively new field of investigation in the scientific community. With the ultimate goal of understanding how humans decide between one path and another, simpler models such as Drosophila Melanogaster, the common fruit fly, are often utilized as a way of determining the neural circuits involved in these decision-making processes. One of the most important decisions flies make is the decision of where to lay their eggs (oviposit). Choosing the proper substrate upon which to lay eggs is a crucial decision that can ultimately impact their fecundity. This paper investigates the …


Promoting Resilience In Self-Management (Prism): Adverse Childhood Experiences And Impacts On Emotion Regulation, Kasey Ann Macedo Apr 2020

Promoting Resilience In Self-Management (Prism): Adverse Childhood Experiences And Impacts On Emotion Regulation, Kasey Ann Macedo

Honors Scholar Theses

PRISM (Promoting Resilience in Self-Management) is a mindfulness-based intervention that aims to strengthen emotion regulation skills among individuals by employing cognitive behavioral therapy components. The purpose of the current study is to identify the relationship between adverse childhood experiences (ACEs) and depression, as well as to examine the changes in emotion regulation strategies of participants by comparing pre and post test data. The participants were voluntarily recruited from the Cornerstone Foundation, a homeless shelter, food pantry, and community center in Vernon, CT. The 13 participants completed PRISM through four weeks of two-hour workshop sessions in a small-group format. Results indicate …


Development And Psychometrics Of The English Version Of The Itch Cognitions Questionnaire, Carolyn J. Heckman, Christina Schut, Mary Riley, Anke Ehlers, Rodrigo Valdes-Rodriguez, Jörg Kupfer, Uwe Gieler, Jerod L. Stapleton Mar 2020

Development And Psychometrics Of The English Version Of The Itch Cognitions Questionnaire, Carolyn J. Heckman, Christina Schut, Mary Riley, Anke Ehlers, Rodrigo Valdes-Rodriguez, Jörg Kupfer, Uwe Gieler, Jerod L. Stapleton

Health, Behavior & Society Faculty Publications

BACKGROUND: The aim of this study was to validate the English version of the Itch Cognition Questionnaire in a sample of patients with chronic itch due to psoriasis or atopic dermatitis. An English-language version of an instrument assessing itch-related cognitions is needed since cognitions can contribute to a worsening of itch, and chronic itch is prevalent in English-speaking counties and internationally.

METHODS: The German Itch Cognitions Questionnaire was translated into English, and cognitive interviewing was conducted to finalize item wording. Internal and test-retest reliability, item discrimination, responsiveness to change, and construct, convergent, and discriminant validity were assessed in a national …


Variable Magnitude And Frequency Financial Reinforcement Is Effective At Increasing Adults’ Free-Living Physical Activity, Vincent Berardi, Melbourne Hovell, Jane C. Hurley, Christine B. Phillips, John Belletierre, Michael Todd, Marc A. Adams Mar 2020

Variable Magnitude And Frequency Financial Reinforcement Is Effective At Increasing Adults’ Free-Living Physical Activity, Vincent Berardi, Melbourne Hovell, Jane C. Hurley, Christine B. Phillips, John Belletierre, Michael Todd, Marc A. Adams

Psychology Faculty Articles and Research

Financial rewards can increase health behaviors, but little research has quantified the effects of different reinforcement schedules on this process. This analysis compares the average moderate-to-vigorous physical activity (MVPA) associated with six distinct positive reinforcement schedules implemented within a physical activity promotion clinical trial. In this trial, participants (N = 512) wore an accelerometer for 1 year and were prescribed one of two types of MVPA goals: a static 30-min goal or an adaptive goal based on the MVPA produced over the previous 9 days. As participants met goals, they transitioned through a sequence of reinforcement stages, beginning with …


“He’S Not Marrying My Daughter”: Stigma Against People In Recovery From Substance Use Disorder, Austin Mcneill Brown Feb 2020

“He’S Not Marrying My Daughter”: Stigma Against People In Recovery From Substance Use Disorder, Austin Mcneill Brown

Population Health Research Brief Series

Substance use disorders are among the most stigmatized health conditions in the U.S. This research brief examines how the language we use to describe people with substance use disorders impact how they are perceived and how willing we are to accept them into our social and professional circles.


Loss Of Self In Dissociation In Prostitution; Recovery Of Self In Connection To Horses: A Survivor's Journey, Sandra Norak Feb 2020

Loss Of Self In Dissociation In Prostitution; Recovery Of Self In Connection To Horses: A Survivor's Journey, Sandra Norak

Dignity: A Journal of Analysis of Exploitation and Violence

This narrative is about dissociation in the lives of women who have been exploited through prostitution. When we speak about prostitution, we do not speak often enough about the dissociation needed for women and girls to survive sexual exploitation. The author challenges the wisdom of governments such as Germany that legalize prostitution, treating it as a “job” and ignoring the violence and subsequent dissociation in women. The author describes her personal journey, explaining how women are traumatized even after the first commercial sex act, which is a sexual assault. They dissociate which makes their lives bearable, but they fail to …


The Missing Moral Dimension: Perceptions Of Transgressions And The Moderating Role Of Moral Foundations On Psychological Distress, Hannah Reas Jan 2020

The Missing Moral Dimension: Perceptions Of Transgressions And The Moderating Role Of Moral Foundations On Psychological Distress, Hannah Reas

Clinical Psychology Dissertations

Anxiety and depression can be represented on a dimensional spectrum of negative affect, broadly termed psychological distress. Research has identified several factors that maintain negative emotion, but have neglected the possibility that individuals’ interpretations of moral issues in the larger macro-system affects their level of distress. Thus, the current study investigated the role of perceptions of moral transgressions, or cognitive interpretations of stimuli (“transgressions”) that violate beliefs about right and wrong, as a predictor of psychological distress. Furthermore, this study tested how perceptions of moral transgressions vary as a function of individuals’ own moral intuitions, or moral foundations. Participants ( …


Analytic Hierarchy Process: An Innovative Technique For Culturally Tailoring Evidence-Based Interventions To Reduce Health Disparities, Jaime A. Corvin, Isabella Chan, Claudia X. Aguado, Ian Dollman, Junius Gonzales Jan 2020

Analytic Hierarchy Process: An Innovative Technique For Culturally Tailoring Evidence-Based Interventions To Reduce Health Disparities, Jaime A. Corvin, Isabella Chan, Claudia X. Aguado, Ian Dollman, Junius Gonzales

Publications from Provost Junius J. Gonzales

Latinos in the United States represent a disproportionate burden of illness and disease and face barriers to accessing health care and related resources. Culturally tailored, evidence-based interventions hold promise in addressing many of these challenges. Yet, ensuring patient voice is vital in the successful development and implementation of such interventions. Thus, this paper examines the application of analytic hierarchy process (AHP) to inform the augmentation and implementation of an evidence-based chronic disease self-management programme for underserved Latinos living with both minor depression and chronic illness. The process of AHP allows for direct input from the individuals that would utilize such …


Measuring The Effects Of Lobinaline-N-Bioxide (419) On Alcohol Consumption, Nicotine Locomotor Sensitization, And Conditioned Place Preference In Mice And Rats, Cocanut M. Suhail Jan 2020

Measuring The Effects Of Lobinaline-N-Bioxide (419) On Alcohol Consumption, Nicotine Locomotor Sensitization, And Conditioned Place Preference In Mice And Rats, Cocanut M. Suhail

Theses and Dissertations--Medical Sciences

Objective: Novel drug 419 was examined to see the effect it has in vivo mice and rats on alcohol consumption, nicotine locomotor sensitization, and conditioned place preference (CPP) models regarding behavioral tests on dopamine transporter activity.

Methods: Mice and rats were used to see how they react to the drug 419 and control vehicle, in each of the models. The animals were assessed to pre- and post- drug administration of novel drug 419. We examined each model to see the association between how drug 419 will help with treating drug abuse.

Results: We found that in alcohol consumption model the …