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Schizophrenia

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Articles 151 - 162 of 162

Full-Text Articles in Psychiatry and Psychology

Response, Remission & Recovery: Need To Review Outcome Measures For Schizophrenia, Amresh Shrivastava, Nilesh Shah Jan 2008

Response, Remission & Recovery: Need To Review Outcome Measures For Schizophrenia, Amresh Shrivastava, Nilesh Shah

Psychiatry Publications

Schizophrenia is a complex neurobehavioral disorder known to be associated with poor outcome. It causes significant disability in patients and burden of care amongst relatives. Outcome in developing countries has been reported to be far better than western world, which has come into scientific scanner recently. Wide gap exists between expectations of outcome amongst patients, relatives, caregivers and professionals, which is possibly because of limitations in measurements tools. Significant number of patients remain marginalized without improvement in social & occupational functioning preventing their integration into mainstream of society despite 'clinically reported good outcome' and significant advancement in treatments. The contemporary …


The Effects Of Nicotine Conditioned Place Preference In D2 Primed Adolescent Rats: Age-Related And Gender Effects., Yoko Emily Ogawa Aug 2007

The Effects Of Nicotine Conditioned Place Preference In D2 Primed Adolescent Rats: Age-Related And Gender Effects., Yoko Emily Ogawa

Electronic Theses and Dissertations

This study investigated nicotine conditioned place preference (CPP) in two different ages of adolescence using a rodent model of schizophrenia. Both 2- and 3-chambered CPP apparatuses were used to test whether the CPP was due to an aversion to the white chamber. Animals were neontally treated with the dopamine D2/D3 agonist, quinpirole, or saline and raised to either early postweanling age (P 22) or adolescence (P 29). Rats were conditioned to prefer the white chamber using nicotine. Results showed that nicotine induced CPP and appeared to alleviate an increased stress response in D2 primed animals, which …


Nicotine Sensitization In A Rodent Model Of Schizophrenia: A Comparison Of Adolescents, Adults, And Neurotrophic Factors., Marla Kay Perna May 2007

Nicotine Sensitization In A Rodent Model Of Schizophrenia: A Comparison Of Adolescents, Adults, And Neurotrophic Factors., Marla Kay Perna

Electronic Theses and Dissertations

The behavioral effects of nicotine on locomotor activity in a rodent model of psychosis were analyzed. This model is based on neonatal quinpriole treatment (a dopamine D2/D3 agonist) which causes increased D2 receptor sensitivity, a phenomenon known as D2 priming that is common in schizophrenia. D2-primed adolescent rats did not demonstrate nicotine-induced hypoactivity early in training, and males demonstrated more rapid sensitization to nicotine as compared to controls administered nicotine. D2-primed females administered nicotine demonstrated increased stereotypic behavior. D2-primed adult rats given nicotine demonstrated significantly more robust sensitization to nicotine than controls given nicotine. Brain-derived neurotrophic factor (BDNF) was analyzed …


The Saint Of Worcester: Why Pilgrims Visit Audrey Santo, Mathew N. Schmalz Feb 2007

The Saint Of Worcester: Why Pilgrims Visit Audrey Santo, Mathew N. Schmalz

Religious Studies Faculty Scholarship

No abstract provided.


Schizophrenia: General Findings And Current Status, Amresh Srivastava Feb 2007

Schizophrenia: General Findings And Current Status, Amresh Srivastava

Psychiatry Presentations

No abstract provided.


Cognition As An Outcome Measure In Schizophrenia, Amresh Srivastava Jan 2007

Cognition As An Outcome Measure In Schizophrenia, Amresh Srivastava

Psychiatry Presentations

No abstract provided.


Atypical Antipsychotics And Cognitive Enhancement In Schizophrenia: The Current Status, Amresh Srivastava Jan 2007

Atypical Antipsychotics And Cognitive Enhancement In Schizophrenia: The Current Status, Amresh Srivastava

Psychiatry Presentations

No abstract provided.


Histories Of Childhood Maltreatment In Schizophrenia: Relationships With Premorbid Functioning, Symptomatology, And Cognitive Deficits, Lindsay S. Schenkel, William D. Spaulding, David Dilillo, Steven M. Silverstein Apr 2005

Histories Of Childhood Maltreatment In Schizophrenia: Relationships With Premorbid Functioning, Symptomatology, And Cognitive Deficits, Lindsay S. Schenkel, William D. Spaulding, David Dilillo, Steven M. Silverstein

Department of Psychology: Faculty Publications

A number of studies have demonstrated an increased rate of histories of childhood maltreatment among adults with serious mental illness. The present investigation documented the presence of childhood maltreatment in a sample of 40 psychiatric inpatients with schizophrenia spectrum disorders. The type (neglect, physical abuse, sexual abuse), duration, and severity of childhood maltreatment was examined along with measures of premorbid functioning, current symptomatology, and cognitive functioning. Participants with histories of maltreatment were significantly more likely to have poorer peer relationships in childhood, more diffi culty in school, an earlier age at first hospitalization, more previous hospitalizations, elevated symptoms of anxiety, …


Would Smokers With Schizophrenia Benefit From A More Flexible Approach To Smoking Treatment?, Dennis E. Mcchargue, Susy B. Gulliver, Brian Hitsman Jun 2002

Would Smokers With Schizophrenia Benefit From A More Flexible Approach To Smoking Treatment?, Dennis E. Mcchargue, Susy B. Gulliver, Brian Hitsman

Department of Psychology: Faculty Publications

We evaluated literature that addresses the notion that flexible smoking treatment approaches are warranted for smokers with a diagnosis of schizophrenia. Understanding the biological and psychological mechanisms that increase the likelihood of smoking and decrease the motivation to quit for these individuals is addressed within the framework of a neurobiological model. We provide a brief overview of the limited smoking cessation treatment literature for patients with schizophrenia and compare abstinence-focused versus reduction-focused treatment modalities. The potential utility of the reduction-focused approach to tobacco treatment for these smokers is evaluated. Suggestions for future research to address the utility and efficacy of …


Unbuckling The Chemical Straitjacket: The Legal Significance Of Recent Advances In The Pharmacological Treatment Of Psychosis, Douglas Mossman Md Jan 2002

Unbuckling The Chemical Straitjacket: The Legal Significance Of Recent Advances In The Pharmacological Treatment Of Psychosis, Douglas Mossman Md

Faculty Articles and Other Publications

Antipsychotic medications figure prominently in the rapidly-growing field of mental disability law. Although the properties of antipsychotic medications are medical matters, legal scholars, judges, and practicing attorneys often need to understand what these drugs do. Yet the legal database - the principal or sole information source cited and consulted by legal thinkers - is often a source of confusion or misinformation about the actions of antipsychotic drugs and the scientific basis for prescribing them. The potential for misunderstanding antipsychotic treatment has increased since the arrival of "novel" or "aytpical" antipsychotic drugs, which cause fewer side effects than drugs that were …


Schizophrenia: A Critical Examination, Charles A. Sanislow, Robert C. Carson Dec 2000

Schizophrenia: A Critical Examination, Charles A. Sanislow, Robert C. Carson

Charles A. Sanislow, Ph.D.

No abstract provided.


The Schizophrenias, Robert Carson, Charles Sanislow Dec 1993

The Schizophrenias, Robert Carson, Charles Sanislow

Charles A. Sanislow

No abstract provided.