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Substance Abuse and Addiction Commons

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Full-Text Articles in Substance Abuse and Addiction

From Drug Use To Dependence: A Multiparametric Approach, Olga A. Vsevolozhskaya, James C. Anthony Jun 2014

From Drug Use To Dependence: A Multiparametric Approach, Olga A. Vsevolozhskaya, James C. Anthony

Olga A. Vsevolozhskaya

One of the hallmarks of a drug dependence (DD) process is an escalation in rate of drug self-administration (DSA). We seek to extend current biostatistical approaches for epidemiological research on drug dependence processes via an investigation of a four-parameter dose-effect curve (DEC).


Confidence Interval Estimation In R-Das: State-Level Estimates For Extra-Medical Use Of Prescription Pain Relievers, Olga A. Vsevolozhskaya, James C. Anthony Mar 2014

Confidence Interval Estimation In R-Das: State-Level Estimates For Extra-Medical Use Of Prescription Pain Relievers, Olga A. Vsevolozhskaya, James C. Anthony

Olga A. Vsevolozhskaya

The specific methodological aims of our research are: 1) to clarify statistical inference procedures used by R-DAS to produce confidence interval estimates; 2) to review a simple solution to some of the research questions not currently addressed by R-DAS (i.e., with respect to tests of significance); and 3) to describe how in certain situations the percentages and the corresponding standard errors, which are suppressed from the R-DAS output due to the confidentiality concerns can be estimated “by hand”.