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Full-Text Articles in Rheumatology
Teriparatide And Its Bone Healing Power, Aneeta J. Joseph, Jesus L. Penabad, Antonio Pinero-Pilona
Teriparatide And Its Bone Healing Power, Aneeta J. Joseph, Jesus L. Penabad, Antonio Pinero-Pilona
West Florida Division Virtual Research Day 2020
Teriparatide, a parathyroid hormone analog, is an important anabolic agent approved by the U.S. Food and Drug Administration to increase bone mineral density in osteoporotic patients. Parathyroid hormone (PTH) regulates calcium, phosphate, and active vitamin-D metabolites. The amino terminal peptide fragments of PTH has been known to increase bone mass and are being used in clinical practice for osteoporosis management.3 Teriparatide increases bone density of lumbar spine and femoral neck, and decreases the risk of vertebral and non-vertebral fractures both in postmenopausal women and men. It is also known to prevent fractures in patients with osteoporosis and promote healing of …
Vitamin D Deficiency And Perceived Pain, Theodore Korty, Adam Grunbaum, Ken Baxa, Olu Oyesanmi
Vitamin D Deficiency And Perceived Pain, Theodore Korty, Adam Grunbaum, Ken Baxa, Olu Oyesanmi
West Florida Division Virtual Research Day 2020
Vitamin D deficiency has been shown to contribute to the onset of musculoskeletal pain, headaches, and fatigue (1, 2). Deficient levels of calcium phosphate have been linked to musculoskeletal pain associated with vitamin D deficiency (3). Low levels of calcium phosphate may result in an inadequately mineralized bone matrix, and normalization of vitamin D levels should help to diminish symptoms of pain by correcting suboptimal mineralization of bone matrix (3). One prior study of patients who underwent orthopedic procedures (including treatment of vertebral compression fractures, Colle’s fractures, hip & knee arthroplasty, ligament repair, and meniscal repair), showed that 44% (n …