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Zucker School of Medicine at Hofstra/Northwell
Computed tomography perfusion;; deconvolution;; low-dose;; radiation dose;; safety;; regularization;; tensor total variation;; cerebral-blood-flow;; high-resolution measurement;; tracer bolus passages;; image quality;; acute stroke;; brain;; tomography;; noise;; quantification;; reconstruction;; Computer Science;; Engineering;; Imaging Science & Photographic;; Technology;; Radiology
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Full-Text Articles in Radiology
Robust Low-Dose Ct Perfusion Deconvolution Via Tensor Total-Variation Regularization, R. G. Fang, S. T. Zhang, T. H. Chen, P. C. Sanelli
Robust Low-Dose Ct Perfusion Deconvolution Via Tensor Total-Variation Regularization, R. G. Fang, S. T. Zhang, T. H. Chen, P. C. Sanelli
Journal Articles
Acute brain diseases such as acute strokes and transit ischemic attacks are the leading causes of mortality and morbidity worldwide, responsible for 9% of total death every year. "Time is brain" is a widely accepted concept in acute cerebrovascular disease treatment. Efficient and accurate computational framework for hemodynamic parameters estimation can save critical time for thrombolytic therapy. Meanwhile the high level of accumulated radiation dosage due to continuous image acquisition in CT perfusion (CTP) raised concerns on patient safety and public health. However, low-radiation leads to increased noise and artifacts which require more sophisticated and time-consuming algorithms for robust estimation. …