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Full-Text Articles in Plastic Surgery
Effect Of Native Type I Collagen With Polyhexamethylene Biguanide Antimicrobial On Wounds: Interim Registry Results., Michael A Bain, Kerry T Thibodeaux, Marcus S Speyrer, Emily Carlson, George John Koullias
Effect Of Native Type I Collagen With Polyhexamethylene Biguanide Antimicrobial On Wounds: Interim Registry Results., Michael A Bain, Kerry T Thibodeaux, Marcus S Speyrer, Emily Carlson, George John Koullias
Articles, Abstracts, and Reports
Background: Biofilm can impair wound healing by maintaining an elevated, but ineffective, inflammatory state. This article describes interim results from the prospective RESPOND postmarketing registry evaluating the use of a native type 1, porcine collagen matrix with the embedded antimicrobial polyhexamethylene biguanide (PCMP) in the management of chronic wounds.
Methods: Adults ≥18 years of age with ≥1 appropriate wound were eligible for inclusion. Data that were final on January 26, 2018 were included in this analysis. At week 0, wounds were cleaned, debrided, and prepared as necessary and PCMP was applied, with a dressing to fix it in place. Patients …