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Articles 1 - 4 of 4
Full-Text Articles in Plastic Surgery
Dermal Collagen Matrices For Ventral Hernia Repair: Comparative Analysis In A Rat Model, G. Broderick, Joyce Mcintyre, M. Noury, Heather Strom, Charles Psoinos, A. Christakas, Kristen Billiar, Zachary Hurwitz, Janice Lalikos, Ronald Ignotz, Raymond Dunn
Dermal Collagen Matrices For Ventral Hernia Repair: Comparative Analysis In A Rat Model, G. Broderick, Joyce Mcintyre, M. Noury, Heather Strom, Charles Psoinos, A. Christakas, Kristen Billiar, Zachary Hurwitz, Janice Lalikos, Ronald Ignotz, Raymond Dunn
Kristen L. Billiar
PURPOSE: The purpose of this study was to compare inflammatory responses, tissue integration, and strength of the acellular dermal collagen matrices AlloDerm((R))* Regenerative Tissue Matrix, Permacol**Surgical Implant (Permacol), and CollaMend*** Implant in a rat model for ventral hernia repair.
METHODS: Rats were randomized into four groups and abdominal wall defects repaired with an inlay graft of AlloDerm, Permacol, or CollaMend. Rats were sacrificed at six time points and the defect area was removed and analyzed for tissue integration and physical strength.
RESULTS: Variable cell infiltration was seen for the three implant groups. At of the all time points examined, cellular …
Advanced Plastic Surgery Techniques For Soft Tissue Coverage Of The Diabetic Foot., Thomas Zgonis, John Stapleton, Thomas S Roukis
Advanced Plastic Surgery Techniques For Soft Tissue Coverage Of The Diabetic Foot., Thomas Zgonis, John Stapleton, Thomas S Roukis
John J Stapleton DPM, FACFAS
Obtaining stable, durable, and functional wound closure of a diabetic foot wound or open pedal amputation through plastic surgical techniques is essential to limit the potential for repeated ulceration, infection, and "supra-pedal" amputation. Myriad conservative and surgical techniques can be used to obtain wound closure. The authors discuss their approach and present operative pearls for their most commonly employed plastic surgical techniques to provide adequate soft tissue coverage of diabetic foot wounds. Emphasis is placed on the techniques necessary to perform these procedures and the surgical thought process involved in closing diabetic foot wounds.
A Case Report Of A Double Advancement Flap Closure Combined With An Ilizarov Technique For The Chronic Plantar Forefoot Ulceration., Ronald Belczyk, John Stapleton, Thomas Zgonis
A Case Report Of A Double Advancement Flap Closure Combined With An Ilizarov Technique For The Chronic Plantar Forefoot Ulceration., Ronald Belczyk, John Stapleton, Thomas Zgonis
John J Stapleton DPM, FACFAS
Soft tissue closure of defects on the plantar surface of the foot continues to be a challenge for the reconstructive surgeon secondarily to the limited number of surgical options and often difficulty of replacing durable and similar soft tissue coverage. Primary closure and skin grafting may not be suitable for the weight-bearing surfaces of the plantar forefoot area, and closure may then be obtained by other means of plastic surgery techniques.
Tensional Forces Influence Gene Expression And Sutural State Of Rat Calvariae In Vitro, S. Tholpady, T. Freyman, Debbie Chachra, R. Ogle
Tensional Forces Influence Gene Expression And Sutural State Of Rat Calvariae In Vitro, S. Tholpady, T. Freyman, Debbie Chachra, R. Ogle
Debbie Chachra
BACKGROUND:
Theories regarding the cause of craniosynostosis that are more than 15 years old cite the role that tensional forces play in the normal and abnormal development of the cranial suture. These theories highlight the effect of stress bands originating from the skull base to the vertex, guiding sutural development.
METHODS:
In this study, the normally fusing posterior intrafrontal suture of the rat was subjected to 3 mN of tensional force for 30 minutes per day. The suture was then assessed for patency, proliferation, apoptosis, and transforming growth factor (TGF)-beta signaling components.
RESULTS:
Sutures that were subjected to tensional force …