Plastic Surgery Commons^™

Decoding Implant-Related Sickness: Unraveling The Complexities Of Breast Implant Illness, Madison M. Stewart

Senior Theses

This thesis investigates the phenomenon of breast implant illness (BII), examining its potential correlation with individual factors such as obesity and poor lifestyle habits. BII, characterized by nonspecific symptoms, is often self-diagnosed by patients influenced by social media and internet sources, leading to requests for implant removal. Conducting a comprehensive meta-analysis, the study scrutinizes existing literature to evaluate the association between BII, obesity, and lifestyle choices. Employing inclusion criteria, peer-reviewed publications are analyzed through systematic review methodology to offer insights into the interplay between BII and adiposity, exploring inflammatory mechanisms and patient behaviors like exercise and smoking. The research aims …

Improvement Of Hair Transplantation In Postcicatracial Alopecia, Maurice Fekry, Ebrahim Awad

Journal of Medicine in Scientific Research

Background Because scarred tissue has less blood flow than normal tissue, fewer hair grafts are taken, and the patient may require many sessions to achieve the acquired density, resulting in a lengthy treatment duration of up to 5 years. The use of platelet-rich plasma (PRP) improves these findings. Patients and methods A prospective randomized-controlled study was conducted on 15 patients with cicatricial alopecia and candidates for follicular unit extraction hair transplantation, with ages between 25 and 60 years. Results Functional and esthetic outcomes were achieved by adding PRP regimen to follicular unit extraction hair transplantation for cases presented to us …

Autologous Fat Transfer For Gluteal Augmentation: A Meta-Analysis Study, Abd El Nasser Mohammed Khallaf, Al-Sayed Hussein El-Sharkawy, Mohammed Mohammed Ali Ahmed

Al-Azhar International Medical Journal

Background: In 1969, Bartels et al. presented the initial description of gluteal augmentation using a breast Cronin prosthesis to treat buttock asymmetry. In recent decades, gluteal fat grafting has seen one of the fastest-growing rates of any cosmetic surgery technique. Objectives: Analyze the published techniques of autologous fat transfer for Buttock augmentation (BBL), and compare different protocols to identify which technique is better in safety and effectiveness over the last 5 years, with demonstration of clinical cases. Subjects and methods: This research was carried out by the Plastic Surgery & Burn Unit of the Al-Azhar University School of Medicine. The …

Skin Graft For Treatment Of Crippled Hypospadias, Ahmed Salem, Khaled Abd Elhaleem Hefny, Mohammad El Sayed Daboos, Amr Mohamed Elsayed

Al-Azhar International Medical Journal

Background: Hypospadias is one of the most frequent birth defects, with an incidence of 1 in every 300 births. After several attempts at hypospadias surgery, the term "crippled hypospadias" has been used to describe patients with unresolved functional problems. Aim of the work: To evaluate the outcome of a two-stage skin graft for treatment of crippled hypospadias regarding graft uptake, penile reconstruction Patients and Method: This clinical study was done in Al-Azhar University Hospital on 15 cases presenting with crippled hypospadias from May 2021 to Oct 2022. After preoperative preparation, all patients were submitted for two-stage skin graft urethroplasty. Results: …

Evaluation Of Boomerang Pattern With J-Torsoplasty For Correction Of Gynecomastia After Massive Weight Loss, Ahmed Nabil Mohamed Emam, Abdel Moneam Hussien Hota, Ahmed Taha Sayed Hassan

Al-Azhar International Medical Journal

Background: Various degree of gynaecomastia with excessive ptosis, nipple malposition, overstretched skin, poorly defined infra-mammary fold, and prominent axillary and lat chest rolls, male chest deformity following significant weight loss is complicated and difficult to treat, so correction methods should allow for the technically correct removal of extra tissue without jeopardizing the blood and nerve supply to the nipple-areola complex. Aim of the work: To ascertain whether J torsoplasty with boomerang excision pattern correction of gynecomastia will result in well-hidden scars and adequate male chest contouring. Patients and methods: The study included 15 patients of bilateral gynecomastia with lateral chest …

Evaluation Of Aesthetic And Oncological Outcomes Of Immediate Versus Delayed Reconstruction In Patients Of Breast Cancer: A Meta-Analysis, Abd-Elrahman Awadeen Abd-Elrahman, Ahmed Mohammed El Mahdy Salem, Hesham Mahmoud Ahmed Emam

Al-Azhar International Medical Journal

Background; with a lifetime probability of up to 10%, breast cancer is considered the utmost prevalent type of cancer among women. One of the key elements for an achieving successful reconstruction is the optimal timing. It is still debated to take a decision choosing between the immediate and the delayed reconstruction.

Aim and objectives: The goal of the present research was the evaluation of both the aesthetic and oncological results of reconstruction: the immediate vs. the delayed, in patients having breast cancer.

Methods: a search in literature was conducted in publications of PUBMED, SienceDirect, EMBASE, Google Scholar and the Cochran …

Innovative Therapeutic Approach To Chemical Burns Produced By Vesicants; An Experimental Study, Cristina Anca Secara, Otilia Liudmila Cinteza, Diana Popescu, Claudia Valentina Popa, Camelia Andreea Hirjeu, Oana Cristina Voinea, Luiza Georgia Serbanescu, Andreea Marilena Pauna, Mihail Tudosie

Journal of Mind and Medical Sciences

Vesicants are compounds that cause severe toxic effects on various tissues. Such chemical action causes tissue necrosis, with clinical expression of skin lesions with a burning character and characteristic blisters. Clinical toxic effects of cutaneous vesicles are correlated with the absorbed dose and exposure time. The goals of the study are to evaluate in vitro the skin toxicity produced by the vesicant chemical compound 2-chloroethyl-ethyl sulfide (CEES), to develop a complex antidote formula, and to optimize the therapeutic efficacy by inclusion in controlled release systems. The experimental protocol aims at the in vitro evaluation of the cytotoxicity of the vesicant …

Biostimulation With Low-Level Laser Therapy And Its Effects On Soft And Hard Tissue Regeneration. Literature Review, Anida Maria Babtan, Aranka Ilea, Claudia Nicoleta Feurdean, Sabino Ceci, Berate Pula, Sebastian Candrea, Daniela Azzollini, Fabio Piras, Luigi Curatoli, Alberto Corriero, Assunta Patano, Francesco Valente, Maria Elena Maggiore, Antonio Mancini, Delia Giovanniello, Ludovica Nucci, Rossella Elia, Adina Sirbu, Nausica Bianca Petrescu, Codruta Mirica, Andrea Galderisi, Filippo Cardarelli

Journal of Mind and Medical Sciences

Objective. Low-Level Laser Therapy encourages the healing process, reduces inflammation and pain. The aim of this study is to identify the impact of Low-Level Laser Therapy on tissue regeneration with special attention to hard tissues and to compare the effect of several wave lengths in the proliferation and differentiation of cells. Methods. The keywords used were “bone regeneration”, “laser therapy”, “photobiomodulation” OR “bio-stimulation”, “Low-Level Laser therapy” OR “LLLT”, “osteoblast proliferation” AND “differentiation”. Results. The bio-stimulation with Low-Level Laser Therapy also seems to interfere with the osseous integration of implants, by increasing its adherence on the bone-implant surfaces. Evidence has shown …

Collagen-Based Biomaterials With Possible Therapeutic Effects, Ramona Mihaela Nedelcuţă, Gigi Călin, Mihai Cristian Nedelcuţă, Vlad Dumitru Baleanu, Dragos Virgil Davitoiu, Bogdan Socea, Bogdan-Petre Stănoiu

Journal of Mind and Medical Sciences

Epidermolysis bullosa (EB) is a rare, serious genetic disease, incurable through the current means. Apart from this initial definition, there was later some ease in the definition of the disease, including the manifestations of toxic epidermal necrolysis and Stevens Johnson syndrome in this entity. In medical practice, there are cases that do not overlap with the description in the literature, thus the treatment must be adapted and personalized to the particularities. We present the case of a female new-born, with "de novo" mutation for the early-onset antenatal epidermolysis and our personalized therapeutic management, based on collagen from bovine corneas by …

Post-Surgical Pyoderma Gangrenosum After Breast Surgery: A Case Series, Jahan Tajran, Daniella Anderson, Arif Chaudhry, Dennis Hammond

Medical Student Research Symposium

Background:

Pyoderma gangrenosum (PG) is a rare inflammatory cutaneous disorder that is thought to be due to innate immune system dysfunction, specifically of neutrophils. PG has been well documented in patients with autoimmune disorders like Ulcerative Colitis and Rheumatoid Arthritis. PG can also present in surgical patients, imitating a potential wound infection and necrotizing fasciitis. Although PG is a diagnosis of exclusion, prompt recognition is essential to attaining desired aesthetic outcomes, especially with breast involvement. We present a case series of four patients who developed PG following breast surgery. We analyze each patient’s medical history, symptoms, wound progression and management …

Recurrent Vulvar Carcinoma: Complex Surgical Treatment Via Perineal Excision And Reconstruction With Musculocutaneous Flap, Dragoș Popa, Cosmin V. Obleagă, Ștefan Paitici, Stelian Ș. Mogoanta, Ionică D. Vîlcea, Pouya Pourgolafshan, Cristian Gheorghe, Manuela I. Vasile, Raluca Câmpeanu, Cecil S. Mirea

Journal of Mind and Medical Sciences

Vulvar cancer is a malignant disease having a low frequency and with well-established surgical and oncological treatments based on the stage of the disease. The most important therapeutic problem encountered is represented by cases of perineal local regional recurrence, which are common in patients with large primary tumors and can occur even if the margins of the resection had no tumoral invasion.

We present a case study of a 64-year-old patient diagnosed one year ago with squamous vulvar carcinoma (G3) for which a vulvectomy was performed after neoadjuvant radiotherapy. The patient later developed local recurrence with invasion of the anal …

The Effects Of Emerging Technology On Healthcare And The Difficulties Of Integration, Skyler J. Pavlish-Carpenter

Honors Undergraduate Theses

Background: Disruptive technology describes technology that is significantly more advanced than previous iterations, such as: 3D printing, genetic manipulation, stem cell research, innovative surgical procedures, and computer-based charting software. These technologies often require extensive overhauls to implement into older systems and must overcome many difficult financial and societal complications before they can be widely used. In a field like healthcare that makes frequent advancements, these difficulties can mean that the technology will not be utilized to its full potential or implemented at all.

Objective: To determine the inhibiting factors that prevent disruptive technology from being implemented in conventional healthcare.

Methods: …

Evaluation Of Tissue-Engineered Tendon Enthesis Polymer Constructs, Joshua A. Bundy Bs, Mary Beth Wade Phd, Hitomi Nakao Md, Phillip Mcclellan Phd, Qing Yu Phd, Robin Jacquet-Childs Ms, William J. Landis Phd

Williams Honors College, Honors Research Projects

Both scientists and clinicians have proposed tissue engineering as the future of medicine. The possibilities for tissue engineering, that is, fabrication of tissues and organs in the laboratory and their translation to patients, appear to be endless, and many believe that this new approach in medicine will result in abolishing many common ailments, injuries, and congenital defects. Injuries to a tendon enthesis, the normal tissue connection between tendon and bone, are of particular concern to clinicians because of their frequency and failure to repair as a result of surgery. While these injuries may not be life threatening, they can certainly …