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Full-Text Articles in Ophthalmology
Anti-Inflammatory Effects Of Apocynin On Dextran Sulfate Sodium-Induced Mouse Colitis Model, Y. J. Hwang, S. J. Nam, W. Chun, S. I. Kim, S. C. Park, C. D. Kang, S. J. Lee
Anti-Inflammatory Effects Of Apocynin On Dextran Sulfate Sodium-Induced Mouse Colitis Model, Y. J. Hwang, S. J. Nam, W. Chun, S. I. Kim, S. C. Park, C. D. Kang, S. J. Lee
Journal Articles
© 2019 Hwang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Background and aim Various drugs have been developed for inflammatory bowel disease (IBD), but still there are limitations in the treatment due to the insufficient responses and significant adverse effects of immunosuppressant. Apocynin is an NADPH-oxidase inhibitor with established safety profiles. We aimed to investigate the protective efficacy of apocynin in IBD using chemicalinduced mouse colitis model. Method We induced experimental …
Ischemic Necrosis Caused By Retroanastomotic Hernia After Subtotal Gastrectomy, S. H. Lee, S. C. Park, S. J. Lee, C. D. Kang, S. J. Nam, S. Y. Lee, S. K. Hong, S. K. Lee
Ischemic Necrosis Caused By Retroanastomotic Hernia After Subtotal Gastrectomy, S. H. Lee, S. C. Park, S. J. Lee, C. D. Kang, S. J. Nam, S. Y. Lee, S. K. Hong, S. K. Lee
Journal Articles
After gastrojejunostomy, a small space can occur between the jejunum at the anastomosis site, the transverse mesocolon, and retroperitoneum, which may cause an intestinal hernia. This report presents a rare case of intestinal ischemic necrosis caused by retroanastomotic hernia after subtotal gastrectomy. A 56-year-old male was admitted to Kangwon National University Hospital with melena, abdominal pain, and nausea. His only relevant medical history was gastrectomy due to stomach cancer. Endoscopic findings revealed subtotal gastrectomy with Billroth-II reconstruction and a bluish edematous mucosal change with necrotic tissue in afferent and efferent loops including the anastomosis site. Abdominopelvic CT showed strangulation of …
Differential Bacterial Colonization And Biofilm Formation On Punctal Occluders, M. Hadjiargyrou, E. D. Donnenfeld, L. M. Grillo, H. D. Perry
Differential Bacterial Colonization And Biofilm Formation On Punctal Occluders, M. Hadjiargyrou, E. D. Donnenfeld, L. M. Grillo, H. D. Perry
Journal Articles
© 2019 by the authors. Dry eye is a common condition that is treated primarily by topical lubricants, immunomodulation, and a variety of punctal and canalicular plugs (occluders). Biofilm formation has been reported as an ongoing problem with the clinical use of occluders. In order to explore the role of biofilm formation on occluders, we tested the bacteria strain, Staphylococcus aureus, with three different types of occluders, Delta R , Odyssey R , and Alphamed R . Scanning electron microscopy (SEM) of these occluders revealed a variation in surface appearance, with Odyssey R being the smoothest (but with grooves), followed …
Imi – Defining And Classifying Myopia: A Proposed Set Of Standards For Clinical And Epidemiologic Studies, D. I. Flitcroft, M. He, J. B. Jonas, M. Jong, K. Naidoo, K. Ohno-Matsui, J. Rahi, S. Resnikoff, S. Vitale, L. Yannuzzi
Imi – Defining And Classifying Myopia: A Proposed Set Of Standards For Clinical And Epidemiologic Studies, D. I. Flitcroft, M. He, J. B. Jonas, M. Jong, K. Naidoo, K. Ohno-Matsui, J. Rahi, S. Resnikoff, S. Vitale, L. Yannuzzi
Journal Articles
© 2019 The Authors. PURPOSE. We provide a standardized set of terminology, definitions, and thresholds of myopia and its main ocular complications. METHODS. Critical review of current terminology and choice of myopia thresholds was done to ensure that the proposed standards are appropriate for clinical research purposes, relevant to the underlying biology of myopia, acceptable to researchers in the field, and useful for developing health policy. RESULTS. We recommend that the many descriptive terms of myopia be consolidated into the following descriptive categories: myopia, secondary myopia, axial myopia, and refractive myopia. To provide a framework for research into myopia prevention, …
Influence Of Bacterial Burden On Meibomian Gland Dysfunction And Ocular Surface Disease, A. Nattis, H. D. Perry, E. D. Rosenberg, E. D. Donnenfeld
Influence Of Bacterial Burden On Meibomian Gland Dysfunction And Ocular Surface Disease, A. Nattis, H. D. Perry, E. D. Rosenberg, E. D. Donnenfeld
Journal Articles
© 2019 Nattis et al. Purpose: Bacterial burden on the eyelid margin and within meibomian glands was evaluated for influence on specific ocular surface disease (OSD) markers across the meibomian gland dysfunction (MGD) spectrum. Methods: In this prospective, observational, single-center study, 40 patients were divided into 4 equal groups of 10 that encompassed increasingly worse MGD/OSD categories. All patients answered the standard Ocular Surface Disease Index questionnaire, and underwent tear osmolarity testing (TOT), Schirmer 1, matrix metalloproteinase 9 (MMP-9) testing, meibography, and lissamine green staining. Cultures of eyelid margins and meibomian gland secretions were directly plated on blood, chocolate, and …
Utility Of En-Face Imaging In Diagnosis Of Occult Macular Dystrophy With Rp1l1 Mutation: A Case Series, M. Z. Ruan, S. A. Hussnain, A. Thomas, M. Mansukhani, S. Tsang, L. Yannuzzi
Utility Of En-Face Imaging In Diagnosis Of Occult Macular Dystrophy With Rp1l1 Mutation: A Case Series, M. Z. Ruan, S. A. Hussnain, A. Thomas, M. Mansukhani, S. Tsang, L. Yannuzzi
Journal Articles
© 2019 The Authors Purpose: To report en-face imaging findings at the level of ellipsoid zone (EZ) in two cases of occult macular dystrophy (OMD) with retinitis pigmentosa 1-like 1 (RP1L1) p.Arg45Trp mutation. Observations: In both patients who presented with decreased vision, pupillary examination, intraocular pressure, and anterior examination were normal. Ophthalmoscopic examination showed prominent choroidal marking whereas fundus autofluorescence was unremarkable. Spectral domain optical coherence tomography (SD-OCT) showed subtle gaps between EZ and retinal pigment epithelium (RPE). The photoreceptor disruption became more evident with en-face imaging at the EZ plane. Conclusions and importance: This is a report of two …
Central Serous Chorioretinopathy: Towards An Evidence-Based Treatment Guideline, T. J. Van Rijssen, E. H. Van Dijk, S. Yzer, K. Ohno-Matsui, J. E. Keunen, R. O. Schlingemann, S. Sivaprasad, G. Querques, L. A. Yannuzzi, C. J. F. Boon, +10 Additional Authors
Central Serous Chorioretinopathy: Towards An Evidence-Based Treatment Guideline, T. J. Van Rijssen, E. H. Van Dijk, S. Yzer, K. Ohno-Matsui, J. E. Keunen, R. O. Schlingemann, S. Sivaprasad, G. Querques, L. A. Yannuzzi, C. J. F. Boon, +10 Additional Authors
Journal Articles
© 2019 The Authors Central serous chorioretinopathy (CSC) is a common cause of central vision loss, primarily affecting men 20–60 years of age. To date, no consensus has been reached regarding the classification of CSC, and a wide variety of interventions have been proposed, reflecting the controversy associated with treating this disease. The recent publication of appropriately powered randomised controlled trials such as the PLACE trial, as well as large retrospective, non-randomised treatment studies regarding the treatment of CSC suggest the feasibility of a more evidence-based approach when considering treatment options. The aim of this review is to provide a …
Colonic Diffuse Large B-Cell Lymphoma Hidden In Actinomycosis, S. H. Lee, S. J. Nam, S. J. Lee, S. C. Park, C. D. Kang, D. H. Choi, J. M. Park, S. K. Lee
Colonic Diffuse Large B-Cell Lymphoma Hidden In Actinomycosis, S. H. Lee, S. J. Nam, S. J. Lee, S. C. Park, C. D. Kang, D. H. Choi, J. M. Park, S. K. Lee
Journal Articles
Actinomycosis can mask malignant diseases. This paper reports a case of colonic diffuse large B-cell lymphoma (DLBCL), which was misdiagnosed as abdominal actinomycosis. A 76-year-old woman presented with right flank pain and weight loss. Abdominal CT and colonoscopy revealed a huge ascending colon mass. Despite the initial impression of a malignancy, a colonoscopic biopsy revealed no malignant cells, but sulfur granules and a filamentous organism suggesting actinomycosis. Intravenous penicillin G was administered under the impression of abdominal actinomycosis but her condition deteriorated rapidly. Follow up CT showed markedly increased colon mass and new multiple nodular lesions around the ascending colon. …
Choosing Core Outcomes For Use In Clinical Trials In Ophthalmology: Perspectives From Three Ophthalmology Outcomes Working Groups, I. J. Saldanha, J. T. Le, S. D. Solomon, M. X. Repka, E. K. Akpek, T. Li, N. Afshari, A. Ambrus, H. Perry, A. Wenick, +29 Additional Authors
Choosing Core Outcomes For Use In Clinical Trials In Ophthalmology: Perspectives From Three Ophthalmology Outcomes Working Groups, I. J. Saldanha, J. T. Le, S. D. Solomon, M. X. Repka, E. K. Akpek, T. Li, N. Afshari, A. Ambrus, H. Perry, A. Wenick, +29 Additional Authors
Journal Articles
No abstract provided.
The Fate And Prognostic Implications Of Hyperreflective Crystalline Deposits In Nonneovascular Age-Related Macular Degeneration, S. Fragiotta, P. Fernáandez-Avellaneda, M. P. Breazzano, C. A. Curcio, B. C. Leong, K. Kato, L. A. Yannuzzi, K. B. Freund
The Fate And Prognostic Implications Of Hyperreflective Crystalline Deposits In Nonneovascular Age-Related Macular Degeneration, S. Fragiotta, P. Fernáandez-Avellaneda, M. P. Breazzano, C. A. Curcio, B. C. Leong, K. Kato, L. A. Yannuzzi, K. B. Freund
Journal Articles
© 2019 The Authors. All rights reserved. PURPOSE. To explore patterns of disease progression in nonneovascular age-related macular degeneration (AMD) associated with hyperreflective crystalline deposits (HCDs) in the subretinal pigment epithelium–basal laminar space. METHODS. Retrospective review of medical records, multimodal imaging, and longitudinal eyetracked near-infrared reflectance (NIR) and optical coherence tomography (OCT) spanning years. NIR/OCT images were analyzed with ImageJ software to identify HCD morphology and location. Associated macular complications were reviewed from the time of HCD detection to the most recent follow-up, using NIR/OCT. RESULTS. Thirty-three eyes with HCDs from 33 patients (mean age: 72 ± 7.5 years) had …
Safety And Efficacy Of Amniotic Cytokine Extract In The Treatment Of Dry Eye Disease., E. Yeu, D. F. Goldberg, F. S. Mah, K. A. Beckman, J. I. Luchs, J. D. Solomon, D. E. White, P. K. Gupta
Safety And Efficacy Of Amniotic Cytokine Extract In The Treatment Of Dry Eye Disease., E. Yeu, D. F. Goldberg, F. S. Mah, K. A. Beckman, J. I. Luchs, J. D. Solomon, D. E. White, P. K. Gupta
Journal Articles
No abstract provided.