Ophthalmology Commons^™

Lamina Cribrosa Insertions Into The Sclera Are Sparser, Narrower, And More Slanted In The Anterior Lamina, Fengting Ji, Mohammad R. Islam, Bingrui Wang, Yi Hua, Ian A. Sigal

Mechanical Engineering Faculty Publications and Presentations

Purpose: The lamina cribrosa (LC) depends on the sclera for support. The support must be provided through the LC insertions. Although a continuous insertion over the whole LC periphery is often assumed, LC insertions are actually discrete locations where LC collagenous beams meet the sclera. We hypothesized that LC insertions vary in number, size, and shape by quadrant and depth.

Methods: Coronal cryosections through the full LCs from six healthy monkey eyes were imaged using instant polarized light microscopy. The images were registered into a stack, on which we manually marked LC insertion outlines, nothing their position in-depth and quadrant …