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Obstetrics and Gynecology Commons

Open Access. Powered by Scholars. Published by Universities.®

2005

Cervical neoplasia screening

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Full-Text Articles in Obstetrics and Gynecology

Comparison Of Pap Smear, Visual Inspection With Acetic Acid, Human Papillomavirus Dna-Pcr Testing And Cervicography, H De Vuyst, Patricia Claeys, S Njiru, L Muchiri, Sophia Steyaert, Petra De Sutter, E Van Marck, J Bwayo, Marleen Temmerman May 2005

Comparison Of Pap Smear, Visual Inspection With Acetic Acid, Human Papillomavirus Dna-Pcr Testing And Cervicography, H De Vuyst, Patricia Claeys, S Njiru, L Muchiri, Sophia Steyaert, Petra De Sutter, E Van Marck, J Bwayo, Marleen Temmerman

Obstetrics and Gynaecology, East Africa

Objective: To assess the test qualities of four screening methods to detect cervical intra-epithelial neoplasia in an urban African setting.

Method: Six hundred fiftythree women, attending a family planning clinic in Nairobi (Kenya), underwent four concurrent screening methods: pap smear, visual inspection with acetic acid (VIA), PCR for high risk human papillomavirus (HR HPV) and cervicography. The presence of cervical intra-epithelial neoplasia (CIN) was verified by colposcopy or biopsy.

Result: Sensitivity (for CIN2 or higher) and specificity (to exclude any CIN or cancer) were 83.3% (95% CI [73.6, 93.0]) and 94.6% (95% CI [92.6, 96.5]), respectively, for pap smear; 73.3% …