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Vasopressin Anatomy Of The Mouse Brain, Benjamin D. Rood

Open Access Dissertations

The nine amino acid peptide vasopressin acts as a neurohormone in the periphery and a neurotransmitter/neuromodulator in the central nervous system. Historically, research on vasopressin neurons and their projections to the pituitary has helped lay the groundwork for our understanding of peptidergic neurotransmission. Currently, our research on central vasopressin projections is driving a revolution in our understanding of social behavior. Vasopressin affects a number of social behaviors from social memory to aggression to affiliative behavior, such as pair-bonding. Further, with the addition of more and more transgenic mouse models of disease states, anxiety and depression related disorders, and social behavior …