Internal Medicine Commons^™

Rare Case Of Giant Asymptomatic Left Coronary Artery Aneurysm Of 10 Cm Associated With Coronary Cameral Fistula, Ali Afzal, Mohamad Sharbatji, Hussain Nawaz, Muqeet Siddiqui

Section of Internal Medicine

A giant coronary artery aneurysm (CAA) associated with a coronary cameral fistula is an extremely rare finding. Most cases of CAAs are asymptomatic. The incidence of CAA varies between 0.3% to 5.3%. Due to advancements in diagnostic technologies, the incidence of CAA is on the rise. Even in the modern days of medical science, the clinical course of CAA is still unpredictable and the suitable timing for the treatment of CAA is still open to debate. We reported a case of a giant coronary artery aneurysm in a 38-year-old female, which was 9.4 x 9.7 x 9.2cm in size, arising …

Diagnostic Value Of Gauze Filtration Technique: A Comparison With Conventional Methods In A Diagnostic Laboratory In Pakistan, Naima Maqsood, Aymen Shakeel, Najia Karim Ghanchi, Ahmed Raheem Buksh, ,Feroz Zaheruddin, Ghazala Jabeen, Afsheen Raza, Mohammad A. Beg

Section of Internal Medicine

Background: Intestinal parasites cause significant morbidity and impact human development with an enormous global burden. Diagnosis of intestinal parasites by conventional methods has several limitations. The gauze filtration technique is a relatively simple method that has been shown to identify intestinal parasites with a high sensitivity and specificity. The aim of this study was to determine the diagnostic value of this technique as compared to more conventional methods in a large acclaimed laboratory within Pakistan.

Methods: A total of 50 stool samples collected for routine diagnostic workup from patients age between 2-70 years were collected from the parasitology section of …

Association Of Catechol-Omethyltransferase (Comt Val158met) With Future Risk Of Cardiovascular Disease In Depressed Individuals - A Swedish Population-Based Cohort Study, Aysha Almas, Yvonne Forsell, Vincent Millischer, Jette Möller, Catharina Lavebrat

Section of Internal Medicine

Background: Catechol-O-methyltransferase (COMT Val¹⁵⁸Met) has been implicated in both depression and cardiovascular disease. The purpose of this study was to assess if COMT Val¹⁵⁸Met, which influences the COMT enzyme activity, has an effect on the risk of cardiovascular disease (CVD) in individuals with a history of depression and also to determine if the risk differs depending on gender.

Methods: Data from a longitudinal cohort study of mental health among Swedish adults was used. Depression was assessed twice 3 years apart for each participant, in 1998-2001 and 2001-2003. Saliva DNA was contributed by 4349 (41.7%) of the …

Aspirin In Primary Prevention Of Myocardial Infarction/Angina And Stroke In Hypertensive Patients, Aysha Almas, Muhammad Salman Ghazni, Shahrukh Hashman, Zain Mushtaq

Section of Internal Medicine

No abstract provided.

Letter To The Editor: Digital Dementia-Is Smart Technology Making Us Dumb?, Sanaa Moledina, Adeel Khoja

Section of Internal Medicine

No abstract provided.

A Comprehensive Meta-Analysis Of Stem Cell Therapy For Chronic Angina, Rahman Shah, Samuel B. Latham, Sajjad A. Khan, Muhammad Shahreyar, Inyong Hwang, Ion S. Jovin

Section of Internal Medicine

Background: A substantial proportion of patients with coronary artery disease do not achieve complete revascularization and continue to experience refractory angina despite optimal medical therapy. Recently, stem cell therapy has emerged as a potential therapeutic option for these patients. However, findings of individual trials have been scrutinized because of their small sample sizes and lack of statistical power. Therefore, we conducted an updated comprehensive meta-analysis of available randomized controlled trials (RCTs) with the largest sample size ever reported on this subject.
Hypothesis: In patients with chronic angina stem cell therapy improves clinical outcomes.
Methods: Scientific databases and websites were searched …

Infection Of A Ventricular Septal Defect Patch With Acremonium Species, Nosheen Nasir, Kauser Jabeen, Joveria Farooqi, Binish Arif Sultan, Afia Zafar, Aamir Hameed Khan, Muneer Amanullah, Farheen Ali

Section of Internal Medicine

A ventricular septal defect (VSD) patch infection with Acremonium species isolated from vegetation and blood culture is described. Antifungal treatment was discontinued after 3 months and patient developed relapse. Surgery with prolonged oral voriconazole was instituted with recovery. We emphasize importance of surgery and prolonged therapy to treat such infections.