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Meningoensefalitis Manifestation In Wegener’S Granulomatosis With Anca Negative: Case Report, Triyanti Kurniasari Ananta Putri Sudibyo, Deshinta Putri Mulya, Eko Budiono, Sekar Satiti, Levina Prima Rosalia

Jurnal Penyakit Dalam Indonesia

Wegener’s granulomatosis is a vasculitis that affects small to medium blood vessels, generally occurring at the age of 64- 75 years with an incidence of 8-10 / 1,000,000 people. Meningoencephalitis manifestations are rarely found in Wegener’s granulomatosis with the incidence only in the range of 0-7%. Anti-neutrophil cytoplasmic antibody (ANCA) is often used in diagnosing Wegener’s granulomatosis, but negative ANCA can be found in 10-20% of cases. A 30-year-old man came with a decrease in consciousness. His anamnesis and physical examination showed signs that led to Wegener’s granulomatosis, despite negative ANCA examination results. After getting therapy according to the management …