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A Comparison Of Various Monoclonal Antibodies To The Previous Standard Of Care Chemotherapy In The Treatment Of Advanced-Stage Melanoma, Kevin Verde, Lauren Johnson, Alex Clancy, Ashley Goldberg, Aleia Monden, Priya Philip
A Comparison Of Various Monoclonal Antibodies To The Previous Standard Of Care Chemotherapy In The Treatment Of Advanced-Stage Melanoma, Kevin Verde, Lauren Johnson, Alex Clancy, Ashley Goldberg, Aleia Monden, Priya Philip
Internet Journal of Allied Health Sciences and Practice
In the year 2015, it is estimated that the number of new cases of invasive melanoma will be 42,670 in males and 31,200 in females.1 Melanoma is treatable with early diagnosis; however, more advanced disease has devastating outcomes. For the past decade, two chemotherapy agents, dacarbazine and temozolomide, have been the treatment of choice for advanced stage III or IV melanoma requiring systemic treatment. Interleukin-2 (IL-2) therapy has been used but with serious side effects. More recently, the focus has shifted to monoclonal antibodies and enzyme inhibitors as the main systemic treatment for advanced cutaneous melanoma. This literature review …