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2019

University of Texas Rio Grande Valley

Articles 1 - 2 of 2

Full-Text Articles in Endocrinology, Diabetes, and Metabolism

Expression Of Integrin And Tgfbi In Human Retinal Pericytes, Andrew T C Tsin, Brenda Su, Laura Valdez, Edgar Serrato Jul 2019

Expression Of Integrin And Tgfbi In Human Retinal Pericytes, Andrew T C Tsin, Brenda Su, Laura Valdez, Edgar Serrato

School of Medicine Publications and Presentations

Purpose: The aim for this study is to investigate the expression of integrin α3, β1 and TGF-β induced protein (TGFBI) and the secretion of TGFBI by primary culture of human retinal pericytes (pHRP). Evidence suggests that chronic diabetes associate with HRP apoptosis leading to the development of diabetic retinopathy.

Methods: pHRP (Cell Systems) were cultured in complete media (15mM glucose) in a humidified, 5% CO2, 37°C condition. Cells were seeded at passage 6 to 8 into a 24 well-plate with coverslips or P10 dishes. Cells (85% confluence) media were then replaced by DMEM media with euglycemic glucose (5.5mM) or hyperglycemic …


Pumping Iron - How Do Race And Gender Affect The Risk Of Anemia In A Cohort Of Predominantly Hispanic Heart Failure (Hf) Patients Seen In A Community Hospital In The Rio Grande Valley (Rgv)?, Michael Lapelusa, Andrea M. Cordero-Reyes, Francisco Avellan, Daniella Concha, Laura Garcia, James Hanley Jan 2019

Pumping Iron - How Do Race And Gender Affect The Risk Of Anemia In A Cohort Of Predominantly Hispanic Heart Failure (Hf) Patients Seen In A Community Hospital In The Rio Grande Valley (Rgv)?, Michael Lapelusa, Andrea M. Cordero-Reyes, Francisco Avellan, Daniella Concha, Laura Garcia, James Hanley

School of Medicine Publications and Presentations

Introduction Anemia in patients with heart failure (HF) is common. Data reported shows a variable prevalence ranging from 10-40%. Additionally, it has also been demonstrated that it is associated with poor outcomes. Multiple risk factors have been shown to contribute to the presence of anemia in HF patients (1). We were interested in determining the risk factors for anemia in HF patients in our population in the lower Rio Grande Valley.

Methods We performed a retrospective chart review of patients admitted with a diagnosis of HF (Heart Failure with Preserved Ejection Fraction HFpEF, Heart Failure with Reduced Ejection Fraction HFrEF …