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Full-Text Articles in Endocrinology, Diabetes, and Metabolism
F-2-Isoprostanes As Novel Biomarkers For Type 2 Diabetes: A Review, Ikram Shah Ismail
F-2-Isoprostanes As Novel Biomarkers For Type 2 Diabetes: A Review, Ikram Shah Ismail
Ikram Shah Ismail
Oxidative stress (OS) has been implicated as one of the major underlying mechanisms behind many acute and chronic diseases. However, the measurement of free radicals or their end products is complicated. Isoprostanes, derived from the non-enzymatic peroxidation of arachidonic acid are now considered to be reliable biomarkers of oxidant stress in the human body. Isoprostanes are involved in many of the human diseases such as type 2 diabetes. In type 2 diabetes elevated levels of F-2-Isoprostanes (F-2-IsoPs) have been observed. The measurement of bioactive F-2-IsoPs levels offers a unique noninvasive analytical tool to study the role of free radicals in …
Role Of N-Epsilon-(Carboxymethyl)Lysine In The Development Of Ischemic Heart Disease In Type 2 Diabetes Mellitus, Ikram Shah Ismail
Role Of N-Epsilon-(Carboxymethyl)Lysine In The Development Of Ischemic Heart Disease In Type 2 Diabetes Mellitus, Ikram Shah Ismail
Ikram Shah Ismail
This study aims to determine the levels of N-epsilon-(carboxymethyl)lysine (CML) in patients with Type 2 diabetic patients with and without ischemic heart disease (IHD) and to find for a possible association between circulating CML and a number of clinical parameters including lipids, hemoglobin Ale (HbA1c) and malondialdehyde (NIDA) in Type 2 diabetic 1111) patients. Serum CML levels were measured by enzyme-linked immunosorbent assay using polyclonal anti-CML antibodies. Serum levels of CML and NIDA were assessed in 60 IHD patients with Type 2 diabetes, 43 HID patients without Type 2 diabetes, 64 Type 2 diabetics without IHD, and 80 sex- and …