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Philadelphia College of Osteopathic Medicine

Keloid

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Is The Use Of Triamcinolone (Tac) In Combination With 5-Fluorouracil (5-Fu) More Effective Than Tac Alone In The Treatment Of Keloid Scars?, Jenna A. Barreto Jan 2017

Is The Use Of Triamcinolone (Tac) In Combination With 5-Fluorouracil (5-Fu) More Effective Than Tac Alone In The Treatment Of Keloid Scars?, Jenna A. Barreto

PCOM Physician Assistant Studies Student Scholarship

Objective: The objective of the selective EBM review is to determine whether or not “Is the use of triamcinolone (TAC) in combination with 5-fluorouracil (5-FU) is more effective than TAC alone in the treatment of keloid scars?”

Study Design: Review of two (2) published, randomized control trials (RCT) and one (1) published, observational case control study (OCCS) in 2009 and 2014. All are in English.

Data Sources: The two (2) RCTs and the OCCS. Both were found using PubMed.

Outcomes Measured: Reduction in scar height and evolution of symptoms, specifically pain and pruritus. Other outcomes measured …