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Is Oral Isotretinoin More Effective Than Antibiotics In The Treatment Of Severe Acne In Adults?, Eric Thomas
Is Oral Isotretinoin More Effective Than Antibiotics In The Treatment Of Severe Acne In Adults?, Eric Thomas
PCOM Physician Assistant Studies Student Scholarship
Objective: The objective of this selective EBM review is to determine whether or not the use of oral isotretinoin is more effective than oral antibiotics in the treatment of severe acne.
Study Design: Review of all English language primary studies published after year 2000.
Data Sources: Three randomized control trials all found using PubMed. Outcomes Measured: Total number and percentage change in total acne lesions from baseline at various intervals.
Results: A randomized control trial (RCT) by Gollnick et al. (2001) found that oral isotretinoin was more effective than combination therapy involving minocycline in treating severe …