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Full-Text Articles in Dermatology

Adipocytes And Innate Immunity In Systemic Sclerosis, Nancy Wareing May 2023

Adipocytes And Innate Immunity In Systemic Sclerosis, Nancy Wareing

Dissertations & Theses (Open Access)

Systemic sclerosis (SSc; scleroderma) is a chronic systemic autoimmune and connective tissue disorder characterized by vasculopathy, autoimmune phenomena, and widespread fibrosis. Skin thickening and tightening is the cardinal feature of SSc and is responsible, in part, for the considerable morbidity of this disease. There are currently no targeted treatments for skin manifestations in SSc, primarily due to our fragmented understanding of its pathophysiologic mechanisms. In PART I, we report a previously unappreciated link between aberrant expression of the developmental gene sine oculis homeobox homolog 1 (SIX1) in skin-associated adipocytes in SSc skin and the early loss of dermal white adipose …


Evaluation Of Efficacy And Safety Of Scalp Threading With Polydioxanone (Pdo) Monofilament Threads In The Treatment Of Male Androgenetic Alopecia, Abdel Kareem Im, Ibrahim Mk, Mahmoud E. Sherif Jan 2023

Evaluation Of Efficacy And Safety Of Scalp Threading With Polydioxanone (Pdo) Monofilament Threads In The Treatment Of Male Androgenetic Alopecia, Abdel Kareem Im, Ibrahim Mk, Mahmoud E. Sherif

Al-Azhar International Medical Journal

Background: Male pattern baldness, known as androgenetic alopecia (AGA), is progressive hair loss. The degree of severity, age at onset, and location of hair loss of this polygenetic condition were varied. Polydioxanone (PDO) threads were used for facial rejuvenation, and becoming increasingly popular in hair growth. Aim: to determine polydioxanone monofilamet threads for male patients with crown baldness (vertex androgenetic alopecia) are safe and effective. Subject and Material: In this pilot study, 7 male AGA patients experiencing crown hair (stage III-vertex androgenetic alopecia by the Norwood-Hamilton scale). Polydioxanone monofilament threads were inserted into the dermal layer of the crown, or …