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Articles 1 - 5 of 5
Full-Text Articles in Dermatology
Abca12-Mediated Lipid Transport And Snap29-Dependent Trafficking Of Lamellar Granules Are Crucial For Epidermal Morphogenesis In A Zebrafish Model Of Ichthyosis., Qiaoli Li, Michael Frank, Masashi Akiyama, Shiu-Ying Ho, Hiroshi Shimizu, Christine Thisse, Bernard Thisse, Eli Sprecher, Jouni Uitto
Abca12-Mediated Lipid Transport And Snap29-Dependent Trafficking Of Lamellar Granules Are Crucial For Epidermal Morphogenesis In A Zebrafish Model Of Ichthyosis., Qiaoli Li, Michael Frank, Masashi Akiyama, Shiu-Ying Ho, Hiroshi Shimizu, Christine Thisse, Bernard Thisse, Eli Sprecher, Jouni Uitto
Department of Dermatology and Cutaneous Biology Faculty Papers
Zebrafish (Danio rerio) can serve as a model system to study heritable skin diseases. The skin is rapidly developed during the first 5-6 days of embryonic growth, accompanied by expression of skin-specific genes. Transmission electron microscopy (TEM) of wild-type zebrafish at day 5 reveals a two-cell-layer epidermis separated from the underlying collagenous stroma by a basement membrane with fully developed hemidesmosomes. Scanning electron microscopy (SEM) reveals an ordered surface contour of keratinocytes with discrete microridges. To gain insight into epidermal morphogenesis, we have employed morpholino-mediated knockdown of the abca12 and snap29 genes, which are crucial for secretion of lipids and …
Atypical Lymphocytic Lobular Panniculitis: A Distinct Eentity In The Spectrum Of Cutaneous Lymphoid Dyscrasia, Lusia S. Yi Do, Ms, Nicole Bright Do, Stephen Purcell Do
Atypical Lymphocytic Lobular Panniculitis: A Distinct Eentity In The Spectrum Of Cutaneous Lymphoid Dyscrasia, Lusia S. Yi Do, Ms, Nicole Bright Do, Stephen Purcell Do
Department of Medicine
No abstract provided.
Oral Fixed Drug Eruption Secondary To Isoniazid, Tanya Ermolovich Do, Tatyana Groysman Do
Oral Fixed Drug Eruption Secondary To Isoniazid, Tanya Ermolovich Do, Tatyana Groysman Do
Department of Medicine
No abstract provided.
Plexiform Neurofibroma Associated With Nf1, Stephen M. Purcell Do, Tatyana Groysman Do
Plexiform Neurofibroma Associated With Nf1, Stephen M. Purcell Do, Tatyana Groysman Do
Department of Medicine
No abstract provided.
Progressive Symmetric Erythrokeratoderma, Sevasti Margetas Do, Stephen Purcell Do
Progressive Symmetric Erythrokeratoderma, Sevasti Margetas Do, Stephen Purcell Do
Department of Medicine
No abstract provided.