Anesthesiology Commons^™

A Call To Action Toward Optimizing The Electrical Dose Received By Neural Targets In Spinal Cord Stimulation Therapy For Neuropathic Pain, Krishnan Chakravarthy, Rajiv Reddy, Adnan Al-Kaisy, Thomas Yearwood, Jay S. Grider

Anesthesiology Faculty Publications

Spinal cord stimulation has seen unprecedented growth in new technology in the 50 years since the first subdural implant. As we continue to grow our understanding of spinal cord stimulation and relevant mechanisms of action, novel questions arise as to electrical dosing optimization. Programming adjustment — dose titration — is often a process of trial and error that can be time-consuming and frustrating for both patient and clinician. In this report, we review the current preclinical and clinical knowledge base in order to provide insights that may be helpful in developing more rational approaches to spinal cord stimulation dosing. We …