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Full-Text Articles in Anesthesiology
Blood Volume And Hemoglobin Oxygenation Response Following Electrical Stimulation Of Human Cortex, Minah Suh, Sonya Bahar, Ashesh Mehta, Theodore Schwartz
Blood Volume And Hemoglobin Oxygenation Response Following Electrical Stimulation Of Human Cortex, Minah Suh, Sonya Bahar, Ashesh Mehta, Theodore Schwartz
Physics Faculty Works
No abstract provided.
Low Doses Of Memantine Disrupt Memory In Adult Rats, Catherine Creeley, David Wozniak, Joanne Labruyere, George Taylor, John Olney
Low Doses Of Memantine Disrupt Memory In Adult Rats, Catherine Creeley, David Wozniak, Joanne Labruyere, George Taylor, John Olney
Psychology Faculty Works
Memantine, a drug recently approved for treatment of Alzheimer’s disease, has been characterized as a unique NMDA antagonist that confers protection against excitotoxic neurodegeneration without the serious side effects that other NMDA antagonists are known to cause. In the present study, we determined what dose of memantine is required to protect the adult rat brain against an NMDA receptor-mediated excitotoxic process and then tested that dose and a range of lower doses to determine whether the drug in this dose range is associated with significant side effects. Consistent with previous research, we found that memantine confers a neuroprotective effect beginning …