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Neurosciences Commons

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Articles 1 - 3 of 3

Full-Text Articles in Neurosciences

Investigating Heat Shock Protein 70 As A Binding Partner Of Mk-Styx, And The Role Of Mk-Styx In Neuronal Differentiation, Lauren Elizabeth Rusnak Jan 2013

Investigating Heat Shock Protein 70 As A Binding Partner Of Mk-Styx, And The Role Of Mk-Styx In Neuronal Differentiation, Lauren Elizabeth Rusnak

Dissertations, Theses, and Masters Projects

No abstract provided.


Cumulative Single-Cell Laser Ablation Of Functionally Or Genetically Defined Respiratory Neurons Interrogates Network Properties Of Mammalian Breathing-Related Neural Circuits In Vitro, Xueying Wang Jan 2013

Cumulative Single-Cell Laser Ablation Of Functionally Or Genetically Defined Respiratory Neurons Interrogates Network Properties Of Mammalian Breathing-Related Neural Circuits In Vitro, Xueying Wang

Dissertations, Theses, and Masters Projects

A key feature of many neurodegenerative diseases is the pathological loss of neurons that participate in generating behavior. to mimic the neuronal degeneration procedure of a functioning neural circuit, we designed a computer-automated system that algorithmically detects and sequentially laser-ablates constituent neurons from a neural network with single-cell precision while monitoring the progressive change of the network function in real time. We applied this cell-specific cumulative lesion technique to an advantageous experimental model, the preBotzinger Complex (preBotC), the mammalian respiratory central pattern generator (CPG) that can be retained in thin slice preparations and spontaneously generates breathing-related motor activity in vitro …


The Relationship Between Neural Reorganization And Neuropsychological Functioning In Normal Aging, Jamie Nicole Hershaw Jan 2013

The Relationship Between Neural Reorganization And Neuropsychological Functioning In Normal Aging, Jamie Nicole Hershaw

Dissertations, Theses, and Masters Projects

No abstract provided.