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Screening For Parkinson's Disease With Response Time Batteries: A Pilot Study, Andrew Johnson, Philip Vernon, Quincy Almeida, Linda Grantier, Rene Singarayer, Mandar Jog
Screening For Parkinson's Disease With Response Time Batteries: A Pilot Study, Andrew Johnson, Philip Vernon, Quincy Almeida, Linda Grantier, Rene Singarayer, Mandar Jog
Andrew M. Johnson
Background: Although significant response time deficits (both reaction time and movement time) have been identified in numerous studies of patients with Parkinson's disease (PD), few attempts have been made to evaluate the use of these measures in screening for PD. Methods: Receiver operator characteristic curves were used to identify cutoff scores for a unit-weighted composite of two choice response tasks in a sample of 40 patients and 40 healthy participants. These scores were then cross-validated in an independent sample of 20 patients and 20 healthy participants. Results: The unit-weighted movement time composite demonstrated high sensitivity (90%) and specificity (90%) in …