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Full-Text Articles in Medical Molecular Biology
Unraveling Macrophage Heterogeneity In Erythroblastic Islands, K. G. Seu, J. Papoin, R. Fessler, J. Hom, G. Huang, N. Mohandas, L. Blanc, T. A. Kalfa
Unraveling Macrophage Heterogeneity In Erythroblastic Islands, K. G. Seu, J. Papoin, R. Fessler, J. Hom, G. Huang, N. Mohandas, L. Blanc, T. A. Kalfa
Journal Articles
No abstract provided.
Multifaceted Role Of Neuropilins In The Immune System: Potential Targets For Immunotherapy., Sohini Roy, Arup K. Bag, Rakesh Singh, James E. Talmadge, Surinder K. Batra, Kaustubh Datta
Multifaceted Role Of Neuropilins In The Immune System: Potential Targets For Immunotherapy., Sohini Roy, Arup K. Bag, Rakesh Singh, James E. Talmadge, Surinder K. Batra, Kaustubh Datta
Journal Articles: Biochemistry & Molecular Biology
Neuropilins (NRPs) are non-tyrosine kinase cell surface glycoproteins expressed in all vertebrates and widely conserved across species. The two isoforms, such as neuropilin-1 (NRP1) and neuropilin-2 (NRP2), mainly act as coreceptors for class III Semaphorins and for members of the vascular endothelial growth factor family of molecules and are widely known for their role in a wide array of physiological processes, such as cardiovascular, neuronal development and patterning, angiogenesis, lymphangiogenesis, as well as various clinical disorders. Intriguingly, additional roles for NRPs occur with myeloid and lymphoid cells, in normal physiological as well as different pathological conditions, including cancer, immunological disorders, …