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Full-Text Articles in Medical Genetics
Exploration Of Prostate Cancer Cells: The Significance Of Active Herv, Dakota Shepherd
Exploration Of Prostate Cancer Cells: The Significance Of Active Herv, Dakota Shepherd
Student Scholar Showcase
The second most common cancer in men is prostate cancer. Prostate cancer is traditionally diagnosed by a digital rectal exam. Blood tests can also be used to test for PSA (prostate-specific antigen). These two methods can be used together but can sometimes provide both false negative and false positive results. A new method of testing for prostate cancer could prove to be beneficial. Previous studies have shown that active HERV sequences have been identified in some cancers, including prostate cancer. We hypothesize that the presence of active HERV in prostate cancer lines is significant. In this study, rabbit polyclonal antibodies …
Updates On Epigenetic Alterations To Brca1: Chemosensitivities, Haley Blum
Updates On Epigenetic Alterations To Brca1: Chemosensitivities, Haley Blum
UNO Student Research and Creative Activity Fair
Breast cancer 1, early onset (BRCA1) is a human tumor suppressor gene encoding the BRCA1 protein that maintains genomic integrity. Molecular events may contribute to the loss of BRCA1 function, contributing to site specific tumorigenesis. Loss of BRCA1 function may arise from mutation or epigenetic events. Germline mutations of BRCA1 have been thoroughly implicated in heritable breast and ovarian cancers. More recently, sporadic breast cancer has been shown to be driven by epigenetic alterations to the BRCA1 promoter region, specifically methylation. Breast carcinomas that present with BRCA1 promoter methylation have been associated with triple negative breast cancers, as well …