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Full-Text Articles in Medical Anatomy
Regeneration Of Neurons In Human Brain Tissue; A Revolutionary Concept With Therapeutic Potential, Mackenzie R. Dunn
Regeneration Of Neurons In Human Brain Tissue; A Revolutionary Concept With Therapeutic Potential, Mackenzie R. Dunn
Other Undergraduate Research
There is current research to suggest that endogenous neuronal regeneration, exogenous neuronal stem cell transplantation and glial cell reprogramming could be prospective therapeutic treatments for neurodegeneration and traumatic injury. With these conditions, there is significant brain atrophy, loss of neurons and loss of synaptic connections which can have devastating effects on executive functioning, cognition, learning and memory. This review will examine these modern approaches to adult neurogenesis, and assess the viable mechanisms and future outlook of these three therapies for neurological regenerative medicine.
Cold Exposure Induces Dynamic, Heterogeneous Alterations In Human Brown Adipose Tissue Lipid Content, Crystal L. Coolbaugh, Bruce M. Damon, Emily C. Bush, E Brian Welch, Theodore F. Towse
Cold Exposure Induces Dynamic, Heterogeneous Alterations In Human Brown Adipose Tissue Lipid Content, Crystal L. Coolbaugh, Bruce M. Damon, Emily C. Bush, E Brian Welch, Theodore F. Towse
Peer Reviewed Articles
Brown adipose tissue undergoes a dynamic, heterogeneous response to cold exposure that can include the simultaneous synthesis, uptake, and oxidation of fatty acids. The purpose of this work was to quantify these changes in brown adipose tissue lipid content (fat-signal fraction (FSF)) using fat-water magnetic resonance imaging during individualized cooling to 3 °C above a participant’s shiver threshold. Eight healthy men completed familiarization, perception-based cooling, and MRI-cooling visits. FSF maps of the supraclavicular region were acquired in thermoneutrality and during cooling (59.5 ± 6.5 min). Brown adipose tissue regions of interest were defined, and voxels were grouped into FSF decades …