Open Access. Powered by Scholars. Published by Universities.®
Skin and Connective Tissue Diseases Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Analytical, Diagnostic and Therapeutic Techniques and Equipment (1)
- Biology (1)
- Biomedical (1)
- Cancer Biology (1)
- Cell and Developmental Biology (1)
-
- Chemicals and Drugs (1)
- Electrical and Computer Engineering (1)
- Engineering (1)
- Enzymes and Coenzymes (1)
- Investigative Techniques (1)
- Life Sciences (1)
- Materials Science and Engineering (1)
- Medical Biochemistry (1)
- Medical Sciences (1)
- Nanoscience and Nanotechnology (1)
- Nanotechnology Fabrication (1)
- Polymer and Organic Materials (1)
- Therapeutics (1)
- Translational Medical Research (1)
- Keyword
Articles 1 - 2 of 2
Full-Text Articles in Skin and Connective Tissue Diseases
Towards Stable Electrochemical Sensing For Wearable Wound Monitoring, Sohini Roychoudhury
Towards Stable Electrochemical Sensing For Wearable Wound Monitoring, Sohini Roychoudhury
FIU Electronic Theses and Dissertations
Wearable biosensing has the tremendous advantage of providing point-of-care diagnosis and convenient therapy. In this research, methods to stabilize the electrochemical sensing response from detection of target biomolecules, Uric Acid (UA) and Xanthine, closely linked to wound healing, have been investigated. Different kinds of materials have been explored to address such detection from a wearable, healing platform. Electrochemical sensing modalities have been implemented in the detection of purine metabolites, UA and Xanthine, in the physiologically relevant ranges of the respective biomarkers. A correlation can be drawn between the concentrations of these bio-analytes and wound severity, thus offering probable quantitative insights …
Identification And Phenotypic Plasticity Of Metastatic Cells In A Mouse Model Of Melanoma, Xiaoshuang Li
Identification And Phenotypic Plasticity Of Metastatic Cells In A Mouse Model Of Melanoma, Xiaoshuang Li
FIU Electronic Theses and Dissertations
Melanoma is the deadliest form of skin cancer due to its high propensity to metastasize and resistance to current therapies. We have created a spontaneous mouse model of metastatic melanoma (Dct-Grm1/K5-Edn3) where metastasis to the lungs is 80% penetrant. The primary tumors of these mice present cellular heterogeneity with cells at varying levels of differentiation. The main goal of this study was to determine the metastatic potential of the primary tumor resident Tyrosinase positive cells and evaluate the dynamic phenotypic changes as those cells move from the primary tumors to the sites of metastasis. To accomplish this aim …