Otorhinolaryngologic Diseases Commons^™

Egyptian Clinical Pathway For Post Covid-19 Acute Invasive Fungal Rhinosinusitis, Ashraf Khaled, Ismail Elnashar, Ahmed Hassan Sweed, Ahmaed Elfarouk, Hossam Elsherif, Ahmed Ragab, Zakareya Elraei, Mohamed Elsharnouby, Baleegh Hamdy, Alaa Ghita, Omar Elbanhawy, Reda Kamel

Pan Arab Journal of Rhinology

Acute invasive fungal rhinosinusitis (AIFRS) is a rare but fatal disease, particularly in immune-compromised patients, including those with hematological malignancies, poorly controlled diabetes mellitus (DM), and those who received immunosuppressive treatment following organ transplantation or chemotherapy for solid organ malignancies. Mortality rates remain high, around 50-80%, though some recent studies have shown higher survival rates with early diagnosis and complete surgical resection. Surgical debridement, systemic antifungal therapy, and prompt correction of the underlying systemic disease are necessary for treatment of AIFRS. During the COVID- 19 pandemic, an increased rate of AIFRS was reported in the course of; or following COVID-19 …