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Full-Text Articles in Otorhinolaryngologic Diseases

Aberrant Expression Of Soluble Programmed Death-Ligand 1 And Inducible Costimulator Ligand In Patients With Nasal Polyps, Mohamed M. Osmana, Omnia H.B. El-Badaway, Asmaa M. Zahran, Mohamed A.M. Salem, Ahmed G. Abdelraheemd Feb 2023

Aberrant Expression Of Soluble Programmed Death-Ligand 1 And Inducible Costimulator Ligand In Patients With Nasal Polyps, Mohamed M. Osmana, Omnia H.B. El-Badaway, Asmaa M. Zahran, Mohamed A.M. Salem, Ahmed G. Abdelraheemd

Pan Arab Journal of Rhinology

Aim We aimed to measure the levels of soluble programmed death-ligand 1 (sPD-L1) and soluble inducible costimulator ligand (sICOS-L) in patients with nasal polyps and to compare their levels between a group with allergic rhinitis (AR) with nasal polyps and another with allergic fungal rhinosinusitis (AFRS). The study also aimed to assess the relationship between their levels and disease severity. Patients and methods The study included 35 patients admitted for endoscopic sinus surgery for nasal polyps, who were divided into 17 with AR and 18 with AFRS and 20 controls. Radiologic computed tomography (CT) score of Lund-Mackay was used to …


Topical Application Versus Intraturbinate Injection Of Botulinum Toxin Type A In The Treatment Of Noninfectious Chronic Rhinosinusitis, Naslshah G. Kazem, Mohamed A. Elsaid, Aya L. Hassan, Abdelrahman A. Abdelalim Jan 2023

Topical Application Versus Intraturbinate Injection Of Botulinum Toxin Type A In The Treatment Of Noninfectious Chronic Rhinosinusitis, Naslshah G. Kazem, Mohamed A. Elsaid, Aya L. Hassan, Abdelrahman A. Abdelalim

Pan Arab Journal of Rhinology

Background Chronic rhinosinusitis is a very common disorder caused by chronic inflammation or irritation of nasal mucosa. Objectives The purpose of this study was to evaluate the efficacy and safety of topical application of botulinum toxin type A (BTX-A) compared with intraturbinate injection for the treatment of noninfectious chronic rhinosinusitis. Patients and methods This prospective comparative study was carried out on 30 patients with noninfectious chronic rhinosinusitis. Patients were divided randomly into two groups. BTX-soaked merocel was applied topically in group A (topical group), which included 15 patients. Intraturbinate BTX injection was applied in group B (injected group), which included …


Prevalence Of Allergic Rhinitis Among Healthcare Workers And Its Impact On Their Work: A Cross-Sectional Survey At A Tertiary Healthcare Centre In Pakistan, Moghira Iqbaluddin Siddiqui, Rahim Dhanani, Huzaifa Moiz Aug 2020

Prevalence Of Allergic Rhinitis Among Healthcare Workers And Its Impact On Their Work: A Cross-Sectional Survey At A Tertiary Healthcare Centre In Pakistan, Moghira Iqbaluddin Siddiqui, Rahim Dhanani, Huzaifa Moiz

Section of Otolaryngology, Head & Neck Surgery

A study was conducted to determine the frequency of allergic rhinitis among healthcare professionals and its impact on their work at the Aga Khan University Hospital Karachi Pakistan. Healthcare workers including doctors, nurses, technicians and pharmacists were included. Participants were asked to fill a questionnaire consisting of score for allergic rhinitis (SFAR), and work productivity and activity impairment questionnaires. Out of 167 workers, 101 were males. Mean age of the participants was 29.0 ± 5.9 years. Overall prevalence of allergic rhinitis among healthcare workers was found to be frequency (19.2%). We noted that 13 individuals reported to have missed their …


Is The Use Of Intestinal Helminths Safe And Effective In The Treatment Of Allergic Rhinitis?, Tanner Mccalley Jan 2013

Is The Use Of Intestinal Helminths Safe And Effective In The Treatment Of Allergic Rhinitis?, Tanner Mccalley

PCOM Physician Assistant Studies Student Scholarship

OBJECTIVE: The objective of this EBM review is to determine whether the use of intestinal helminths is safe and effective in the treatment of allergic rhinitis.

STUDY DESIGN: Review of three English language, blinded randomized controlled trials from 2009, 2010, and 2010.

DATA SOURCE: Randomized, controlled, blinded trials comparing the use of intestinal helminths versus visually matched placebo as a treatment for allergic rhinitis found using PubMed and Ovid databases.

OUTCOMES MEASURED: Several different systems were used to evaluate the symptoms or occurrence of AR. Bager et al.2010 uses symptom scores of AR scale of 0 …