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Full-Text Articles in Immune System Diseases
What Is Pfapa And Why Does It Matter?, Dennis J. Baumgardner
What Is Pfapa And Why Does It Matter?, Dennis J. Baumgardner
Journal of Patient-Centered Research and Reviews
PFAPA, the syndrome of periodic fever, aphthous stomatitis, pharyngitis and cervical lymphadentitis, is an uncommon disease of episodic immune dysregulation that usually begins in early childhood. Symptoms occur at regular, predictable intervals, with healthy periods in between, and generally include the namesake signs and various other constitutional symptoms such as fever and fatigue. The etiology is unknown and there is no definitive diagnostic test or treatment. Uncertainty during the period of searching for a diagnosis may be disconcerting to the family and the clinician. Single-dose prednisone is effective for resolving the fever of PFAPA episodes within just a few hours, …
Recurrent Aphthous Stomatitis: Diagnosis And Management In Primary Care, Jillian Hudson
Recurrent Aphthous Stomatitis: Diagnosis And Management In Primary Care, Jillian Hudson
Journal of Patient-Centered Research and Reviews
Recurrent aphthous stomatitis (canker sores) is a very common oral condition that remains incompletely understood. Presentation has been well-classified into minor, major or herpetiform subcategories based on clinical features, but exact etiology is unknown. Because etiology is unclear, treatments are primarily empiric and aimed at symptom reduction rather than prevention or cure. However, there are several methods, both topical and systemic, that can be easily and affordably utilized in the primary care setting.