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51-Year-Old Female With Epistaxis And Generalized Weakness For 2 Months Diagnosed With Rpgn, Meihuan Lin
51-Year-Old Female With Epistaxis And Generalized Weakness For 2 Months Diagnosed With Rpgn, Meihuan Lin
North Texas Research Forum 2023
Rapidly progressive glomerulonephritis (RPGN)’s clinical presentation including acute onset of macroscopic hematuria, decreased urine output, acute onset of hypertension, and edema. Other clinical findings include nephritis presentation on urine analysis with proteinuria, micro and macroscopic hematuria, red blood cells, dysmorphic RBC and RBC casts. Pathological findings characterized extensive crescent formation. Untreated patients can rapidly progress to end-stage kidney disease over a very short periods (days to months). Renal biopsy can further differentiate the types of crescentic glomerulonephritis. There are three major types of RPGN: 1. Anti-glomerular basement membrane (GBM) disease cause by anti-GBM antibodies. It is also associated with pulmonary …