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Full-Text Articles in Bacterial Infections and Mycoses
Chitosan-Gallium Nanocomposite: Synthesis, Characterization And Antibacterial Activity, Samjhana Bhandari
Chitosan-Gallium Nanocomposite: Synthesis, Characterization And Antibacterial Activity, Samjhana Bhandari
Electronic Theses and Dissertations, 2020-
The emergence of multidrug-resistant (MDR) strains of bacteria and the lack of a novel class of antibiotics has become a global health concern. Pseudomonas aeruginosa is one common MDR bacteria responsible for nosocomial infections and related mortality worldwide. It has developed resistance against commonly available antibiotics and is in the WHO's priority list of bacteria for which new antibiotics are desperately needed. Currently there is a growing interest in developing metal and non-metal-based nanoparticles to target multidrug-resistant bacteria. The objective of this study is to evaluate the efficacy of a novel nanocomposite of two non-traditional antimicrobials: a metal (Ga-III) and …
Role Of Rela In Dormancy And Toxr Proteolysis In Vibrio Cholerae, Zachary J. Malaussena
Role Of Rela In Dormancy And Toxr Proteolysis In Vibrio Cholerae, Zachary J. Malaussena
Honors Undergraduate Theses
Vibrio cholerae, the etiological agent of the severe diarrheal disease cholera, is an enteric pathogen that can be found in aquatic ecosystems when not colonizing the human gastrointestinal tract. Under adverse environmental conditions, V. cholerae is capable of entering dormant states that increase its survival during these ecological fluctuations. In these states, V. cholerae slows its metabolic activity and exhibits drastically altered gene expression and morphology. Stressors that lead to entry into these states vary from nutrient limitation, suboptimal pH, or antimicrobials. Cells in these dormant states are highly resistant to antimicrobials and cannot be detected using standard microbiological techniques …