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Bacterial Infections and Mycoses Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
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- Administration, Intravenous (1)
- Administration, Oral (1)
- Adolescent (1)
- Anti-Bacterial Agents (1)
- Catheterization, Peripheral (1)
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- Child Day Care Centers (1)
- Child, Preschool (1)
- Cohort Studies (1)
- Compliment Activation (1)
- Disease Outbreak (1)
- Eculizumab (1)
- Escherichia coli Infections (1)
- Hemolytic anemia (1)
- Hemolytic uremic syndrome (1)
- Hemolytic-Uremic Syndrome (1)
- Humans (1)
- Infant (1)
- Patient Discharge (1)
- Pneumonia (1)
- Retrospective Studies (1)
- Shiga Toxin (1)
- Treatment Failure (1)
- White blood cell (1)
Articles 1 - 2 of 2
Full-Text Articles in Bacterial Infections and Mycoses
Intravenous Versus Oral Antibiotics For Postdischarge Treatment Of Complicated Pneumonia., Samir S. Shah, Rajendu Srivastava, Susan Wu, Jeffrey D. Colvin, Derek J. Williams, Shawn J. Rangel, Waheeda Samady, Suchitra Rao, Christopher Miller, Cynthia Cross, Caitlin Clohessy, Matthew Hall, Russell Localio, Matthew Bryan, Gong Wu, Ron Keren, Pediatric Research In Inpatient Settings Network
Intravenous Versus Oral Antibiotics For Postdischarge Treatment Of Complicated Pneumonia., Samir S. Shah, Rajendu Srivastava, Susan Wu, Jeffrey D. Colvin, Derek J. Williams, Shawn J. Rangel, Waheeda Samady, Suchitra Rao, Christopher Miller, Cynthia Cross, Caitlin Clohessy, Matthew Hall, Russell Localio, Matthew Bryan, Gong Wu, Ron Keren, Pediatric Research In Inpatient Settings Network
Manuscripts, Articles, Book Chapters and Other Papers
BACKGROUND AND OBJECTIVES: Postdischarge treatment of complicated pneumonia includes antibiotics administered intravenously via a peripherally inserted central venous catheter (PICC) or orally. Antibiotics administered via PICC, although effective, may result in serious complications. We compared the effectiveness and treatment-related complications of postdischarge antibiotics delivered by these 2 routes.
METHODS: This multicenter retrospective cohort study included children ≥2 months andadministration, classified as PICC or oral. The primary outcome was treatment failure. Secondary outcomes included PICC complications, adverse drug reactions, other related revisits, and a composite of all 4 outcomes, termed "all related revisits."
RESULTS: Among 2123 children, 281 (13.2%) received antibiotics …
Typical Hus: Evidence Of Acute Phase Complement Activation From A Daycare Outbreak, T M. Brady, C Pruette, L F. Loeffler, Darcy Weidemann, J J. Strouse, E Gavriilaki, R A. Brodsky
Typical Hus: Evidence Of Acute Phase Complement Activation From A Daycare Outbreak, T M. Brady, C Pruette, L F. Loeffler, Darcy Weidemann, J J. Strouse, E Gavriilaki, R A. Brodsky
Manuscripts, Articles, Book Chapters and Other Papers
The clinical manifestations of typical hemolytic uremic syndrome (HUS) encompass a wide spectrum. Despite the potentially severe sequelae from this syndrome, treatment approaches remain supportive. We present the clinical course of a child who contracted Shiga toxin-positive E. coli (STEC) from a daycare center during an outbreak. Utilizing the modified Ham test which is a rapid, serum-based functional assay used to detect activation of the alternative pathway of complement as observed in atypical HUS, patient sera revealed evidence of increased complement activation in the acute phase of the syndrome but not after resolution. Further, this complement activation was attenuated by …