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Full-Text Articles in Bacterial Infections and Mycoses

Involvement Of Interleukin-33/St2 In Myocardial Dysfunction In Murine Model Of Sepsis, Yoonmi Choe Dec 2012

Involvement Of Interleukin-33/St2 In Myocardial Dysfunction In Murine Model Of Sepsis, Yoonmi Choe

Electronic Thesis and Dissertation Repository

The disruption of myocardial extracellular matrix (ECM) has been implicated in myocardial dysfunction during sepsis. However, the underlying mechanism(s) are not clear. Interleukin-33 (IL-33) is a cytokine which regulates collagen synthesis in various cardiac pathologies. The purpose of the present study is to test whether IL-33 contributes to sepsis-induced myocardial dysfunction through regulation of matrix metalloproteinase-9 (MMP-9). The in vivo, feces-induced peritonitis (FIP) in mice and in vitro lipopolysaccharide (LPS) treatments to isolated cardiomyocytes were used. In FIP mice, myocardial IL-33 and MMP-9 expression were increased and myocardial contractility was decreased. Myocardial function in FIP mice was improved when treated …


Isolation Of L4 Ribo-Protein Mutants That Affect The Expression Of Tna Operon Of Escherichia Coli, Soniykha Dhevi Murukan Jan 2012

Isolation Of L4 Ribo-Protein Mutants That Affect The Expression Of Tna Operon Of Escherichia Coli, Soniykha Dhevi Murukan

Summer Community of Scholars Posters (RCEU and HCR Combined Programs)

No abstract provided.


Human Risk Of Infection With Borrelia Burgdorferi, The Lyme Disease Agent, In Eastern United States, Maria A. Diuk-Wasser, Anne Gatewood Hoen, Paul Cislo, Robert Brinkerhoff, Sarah A. Hamer, Michelle Rowland, Roberto Cortinas, Gwenaël Vourc’H, Forrest S. Melton, Graham J. Hickling, Jean I. Tsao, Jonas Bunikis, Alan G. Barbour, Uriel Kitron, Joseph Piesman, Durland Fish Jan 2012

Human Risk Of Infection With Borrelia Burgdorferi, The Lyme Disease Agent, In Eastern United States, Maria A. Diuk-Wasser, Anne Gatewood Hoen, Paul Cislo, Robert Brinkerhoff, Sarah A. Hamer, Michelle Rowland, Roberto Cortinas, Gwenaël Vourc’H, Forrest S. Melton, Graham J. Hickling, Jean I. Tsao, Jonas Bunikis, Alan G. Barbour, Uriel Kitron, Joseph Piesman, Durland Fish

Department of Entomology: Faculty Publications

The geographic pattern of human risk for infection with Borrelia burgdorferi sensu stricto, the tick-borne pathogen that causes Lyme disease, was mapped for the eastern United States. The map is based on standardized field sampling in 304 sites of the density of Ixodes scapularis host-seeking nymphs infected with B. burgdorferi, which is closely associated with human infection risk. Risk factors for the presence and density of infected nymphs were used to model a continuous 8 km × 8 km resolution predictive surface of human risk, including confidence intervals for each pixel. Discontinuous Lyme disease risk foci were identified in …