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Full-Text Articles in Bacterial Infections and Mycoses
Bacillus Anthracis Virulent Plasmid Px02 Genes Found In Large Plasmids Of Two Other Bacillus Species, Vicki A. Luna, Debra S. King, K. Kealy Peak, Frank Reeves, Lea Heberlein-Larson, William Veguilla, L. Heller, Kathleen E. Duncan, Andrew C. Cannons, Philip Amuso, Jacqueline Cattani
Bacillus Anthracis Virulent Plasmid Px02 Genes Found In Large Plasmids Of Two Other Bacillus Species, Vicki A. Luna, Debra S. King, K. Kealy Peak, Frank Reeves, Lea Heberlein-Larson, William Veguilla, L. Heller, Kathleen E. Duncan, Andrew C. Cannons, Philip Amuso, Jacqueline Cattani
Bioelectrics Publications
In order to cause the disease anthrax, Bacillus anthracis requires two plasmids, pX01 and pX02, which carry toxin and capsule genes, respectively, that are used as genetic targets in the laboratory detection of the bacterium. Clinical, forensic, and environmental samples that test positive by PCR protocols established by the Centers for Disease Control and Prevention for B. anthracis are considered to be potentially B. anthracis until confirmed by culture and a secondary battery of tests. We report the presence of 10 genes (acpA, capA, capB, capC, capR, capD, IS1627, ORF 48, ORF 61, and repA) and the sequence for the …
Treponema Denticola In Disseminating Endodontic Infections, F. Foschi, Jacques Izard, H. Sasaki, V. Sambri, C. Prati, R. Müller, P. Stashenko
Treponema Denticola In Disseminating Endodontic Infections, F. Foschi, Jacques Izard, H. Sasaki, V. Sambri, C. Prati, R. Müller, P. Stashenko
Department of Food Science and Technology: Faculty Publications
Treponema denticola is a consensus periodontal pathogen that has recently been associated with endodontic pathology. In this study, the effect of mono-infection of the dental pulp with T. denticola and with polymicrobial “red-complex” organisms (RC) (Porphyromonas gingivalis, Tannerella forsythia, and T. denticola) in inducing disseminating infections in wild-type (WT) and severe-combined-immunodeficiency (SCID) mice was analyzed. After 21 days, a high incidence (5/10) of orofacial abscesses was observed in SCID mice mono-infected with T. denticola, whereas abscesses were rare in SCID mice infected with the red-complex organisms or in wild-type mice. Splenomegaly was …