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Full-Text Articles in Dental Public Health and Education

Differentiation Of Dental Pulp Stem Cells Into Islet-Like Aggregates, Noor Hayaty Abu Kasim Abu Kasim N.H. Apr 2011

Differentiation Of Dental Pulp Stem Cells Into Islet-Like Aggregates, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

The post-natal dental pulp tissue contains a population of multipotent mesenchymal progenitor cells known as dental pulp stromal/stem cells (DPSCs), with high proliferative potential for self-renewal. In this investigation, we explored the potential of DPSCs to differentiate into pancreatic cell lineage resembling islet-like cell aggregates (ICAs). We isolated, propagated, and characterized DPSCs and demonstrated that these could be differentiated into adipogenic, chondrogenic, and osteogenic lineage upon exposure to an appropriate cocktail of differentiating agents. Using a three-step protocol reported previously by our group, we succeeded in obtaining ICAs from DPSCs. The identity of ICAs was confirmed as islets by dithiozone-positive …


3d-Fe Analysis Of Functionally Graded Structured Dental Posts, Noor Hayaty Abu Kasim Abu Kasim N.H. Dec 2010

3d-Fe Analysis Of Functionally Graded Structured Dental Posts, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

This study aimed to compare the biomechanical behaviour of functionally graded structured posts (FGSPs) and homogenous-type posts in simulated models of a maxillary central incisor. Two models of FGSPs consisting of a multilayer xTi-yHA composite design, where zirconia and alumina was added as the first layer for models A and B respectively were compared to homogenous zirconia post (model C) and a titanium post (model D). The amount of Ti and HA in the FGSP models was varied in gradations. 3D-FEA was performed on all models and stress distributions were investigated along the dental post. In addition, interface stresses between …


Inherent Differential Propensity Of Dental Pulp Stem Cells Derived From Human Deciduous And Permanent Teeth, Noor Hayaty Abu Kasim Abu Kasim N.H. Aug 2010

Inherent Differential Propensity Of Dental Pulp Stem Cells Derived From Human Deciduous And Permanent Teeth, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

Introduction: Lately, several new stem cell sources and their effective isolation have been reported that claim to have potential for therapeutic applications. However, it is not yet clear which type of stem cell sources are most potent and best for targeted therapy. Lack of understanding of nature of these cells and their lineage-specific propensity might hinder their full potential. Therefore, understanding the gene expression profile that indicates their lineage-specific proclivity is fundamental to the development of successful cell-based therapies. Methods: We compared proliferation rate, gene expression profile, and lineage-specific propensity of stem cells derived from human deciduous (SCD) and permanent …


The Ball Mill As A Means Of Investigating The Mechanical Failure Of Dental Materials, Noor Hayaty Abu Kasim Abu Kasim N.H. Dec 1995

The Ball Mill As A Means Of Investigating The Mechanical Failure Of Dental Materials, Noor Hayaty Abu Kasim Abu Kasim N.H.

Noor Hayaty Abu Kasim Abu Kasim N.H.

Objective: The main purpose of this paper is to present a new method of predicting clinical performance using mechanical loading in a ball mill. Methods: A series of four experiments (two involving a hybrid composite and one each on orthodontic brackets and bands) is described in which the ball mill was used to subject specimens to mechanical fatigue. Results: A reproducibility study using composite beam specimens showed no significant difference between the Mean Survival Time (MST) in all the three experimental runs (P = 0.42). When subjected to thermal cycling, the MST of the cycled group was 155.0 min compared …