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Dental Materials Commons

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Theses/Dissertations

1972

Animal Experimentation and Research

Articles 1 - 3 of 3

Full-Text Articles in Dental Materials

Marrow Isografts In The Oral Cavity Of Mice, Robert L. Merin Jun 1972

Marrow Isografts In The Oral Cavity Of Mice, Robert L. Merin

Loma Linda University Electronic Theses, Dissertations & Projects

The objectives of this study were to develop an animal model for testing oral bone and marrow transplantation that is adaptable to immunological studies; to determine the effect of an isogeneic graft of cancellous bone and marrow on the healing of surgically created defects; and to determine the fate of grafted isogeneic cancellous bone and marrow transplanted into defects. Fourteen CBA/H mice served as experimental animals and bilateral intraoral defects were prepared. The experimental side received isogeneic graft material while the other side served as a control. Osseous healing was found to be accelerated in the defects receiving graft material …


Microscopic Evaluation Of Topically Applied Chlorhexidine Gluconate On Gingival Wound Healing In Dogs, Robert C. Hirst Jun 1972

Microscopic Evaluation Of Topically Applied Chlorhexidine Gluconate On Gingival Wound Healing In Dogs, Robert C. Hirst

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was to evaluate microscopically the effect of topically applied 2% chlorhexidine gluconate on the healing of gingival wounds in dogs.

One week after the teeth were scaled and polished, seven experimental wound sites were prepared in the facial gingiva adjacent to the four premolars on each side of the maxillary arch in six young Labrador dogs. From this point the dogs were fed a soft plaque-inducing diet. Chlorhexidine solution was applied daily to either the right or left maxillary premolars while on the opposite side of the arch in three dogs the first and second …


The Effect Of Oral Allografts Of Cancellous Bone And Marrow In Mice, George E. Deeb Jun 1972

The Effect Of Oral Allografts Of Cancellous Bone And Marrow In Mice, George E. Deeb

Loma Linda University Electronic Theses, Dissertations & Projects

The purpose of this study was: to develop a model for testing oral bone transplantation; to study the healing of a surgically produced defect with and without the transplantation of strongly allogeneic cancellous bones and marrow; and to determine the fate of the allogenic grafts. Twenty-eight CBA/H mice served as experimental animals. Intra-oral defects were made and in 14 of the animals strongly allogenic cancellous bone and marrow were transplanted. The 14 remaining animals served as controls. It was observed that the healing was delayed in the experimental animals as compared to the controls and that the grafted material was …