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Salivary Iga Depression In Drug-Influenced Gingival Enlargement Among Hypertensive Patients, Muhammad Annurdin Sabarudin, Haslina Taib, Wan Majdiah Wan Mohamad, Siti Lailatul Akmar Zainuddin, Wan Syamimee Wan Ghazali, Ahmad Azhar Misran
Salivary Iga Depression In Drug-Influenced Gingival Enlargement Among Hypertensive Patients, Muhammad Annurdin Sabarudin, Haslina Taib, Wan Majdiah Wan Mohamad, Siti Lailatul Akmar Zainuddin, Wan Syamimee Wan Ghazali, Ahmad Azhar Misran
Journal of Dentistry Indonesia
Drug-influenced gingival enlargement (DIGE) among hypertensive patients is commonly associated with antihypertensive drugs such as calcium channel blockers (CCBs). Immune response alteration is one of the proposed mechanisms for DIGE. Immunoglobulin A (IgA) in saliva which involves in defense mechanism was shown to be affected in patients with DIGE. Objective: This study aimed to determine the association of salivary IgA level with DIGE. Methods: This cross-sectional study comprised 47 hypertensive patients who had consumed antihypertensive drugs for at least 3 months. Twenty-one (44.7%) males and 26 (55.3%) females had participated in this study. Data was analyzed using SPSS version 26.0. …