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Senior Honors Projects, 2010-2019

Heterozygous Advantage

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Full-Text Articles in Speech and Hearing Science

Reflection: Effect Of Age On Auditory Brainstem Responses In Mice With Epha4 Mutations, Erica L. Hoogerland May 2016

Reflection: Effect Of Age On Auditory Brainstem Responses In Mice With Epha4 Mutations, Erica L. Hoogerland

Senior Honors Projects, 2010-2019

Presbycusis, or age-related hearing loss is a condition that affects approximately 40% of the population over 65 years of age (Gates & Mills, 2005). Studying the effects of EphA4 mutations (wild type, heterozygous, and homozygous) mice is fundamental in understanding the relationship between onset of age-related hearing loss, in both the mammalian population and the human population. In order to further understanding of age-related hearing loss, the researchers evaluated thirty-six mice in a preliminary study from two months to nine months of age. Following data analysis, the researchers confirmed the results by continuing a second round of testing. The hearing …