Speech and Hearing Science Commons^™

Advanced Phenotyping Of Otosclerosis In An Ontario Population And Two Large Newfoundland Families, Matthew B. Lucas

Electronic Thesis and Dissertation Repository

Otosclerosis is a relatively common hearing loss disorder characterized by abnormal bone growth in the otic capsule leading to stapes fixation. In approximately half of cases, otosclerosis is inherited as an autosomal dominant trait. Typically, gene discovery efforts rely on surgical confirmation, audiometry and occasionally acoustic reflexes to identify affected cases of otosclerosis within families, requiring that the otosclerosis was at an advanced stage to be detected. This makes it difficult to identify individuals with early otosclerosis. The use of advanced phenotyping to identify cases of otosclerosis was tested in an Ontario otosclerotic population as well as in two large …

Behavioural And Objective Assessment Of Binaural Hearing In Adult Listeners With Acquired Unilateral Conductive Hearing Loss Before And After Middle Ear Surgery, Parvaneh Abbasalipour

Electronic Thesis and Dissertation Repository

In normally hearing listeners, binaural hearing relies on symmetrical input from the two ears. Previous studies on human listeners have assessed the effect of induced unilateral conductive hearing loss (UCHL) during adulthood via earplugging. These experiments indicated initial difficulty in sound localization followed by gradual improvement due to adaptation to the perturbed binaural cues. The limited duration of earplug use does not represent the consequences of chronic UCHL secondary to disease. Furthermore, there is insufficient information regarding the adaptation of binaural hearing abilities after treatment of late-onset UCHL.

The current study assessed the binaural hearing abilities of adult listeners with …