Speech and Hearing Science Commons^™

The Directional Effect Of Target Position On Spatial Selective Auditory Attention, Heesung Park

Dissertations, 2020-current

Spatial selective auditory attention plays a crucial role in listening in a mixture of competing speech sounds. Previous neuroimaging studies have reported alpha band neural activity modulated by auditory attention, along with the alpha lateralization corresponding to attentional focus. A greater cortical representation of the attended speech envelope compared to the ignored speech envelope was also found, a phenomenon known as 'neural speech tracking’. However, little is known about the neural activities when attentional focus is directed on speech sounds from behind the listener, even though understanding speech from behind is a common and essential aspect of daily life. The …

Dynamic Measures Of Referential Communication Reveal Hidden Pragmatic Strengths For Adolescents With Autism Spectrum Disorder, Mariana Schreuders

Senior Honors Projects, 2020-current

The ability to communicate effectively and efficiently while maintaining mutual understanding is a fundamental aspect of human-to-human interaction. Studies have shown that individuals with autism spectrum disorder (ASD) face challenges in areas of social communication skills, such as aspects of referential communication; or the ability to refer to things in such a way that a listener will know what the speaker is describing. The current study used data from a preexisting Barrier study to compare the referential communication abilities of school-aged children with ASD to those of neurotypical children (NT). Referential communication was observed during a barrier task, where participants …

Pre-Pulse Inhibition In Mutated Mice: Studying Compromised Microglial Cells To Discover New Genetic Connections To Autism, Bailey R. Kramarik

Senior Honors Projects, 2020-current

Microglial cells “play a pivotal role in refining neural networks during early critical periods” (Gabriele & Gray, 2020, p. 1). A disturbance in the functioning of these microglial cells contribute to specific characteristics of some neurodevelopmental disorders- including autism spectrum disorder. In this study, we used a mouse model to study disruptions in cell activity, as understanding the biological and genetic background of autism spectrum disorder could help us provide better treatment and therapy options to those diagnosed.

The mutated mice in this experiment have microglial cells with “compromised fractalkine signaling” (Gabriele & Gray, 2020, p. 4-5). We studied multimodal …

The Relationship Between Quality Of Life Outcomes And Social Hearing For Cochlear Implant Recipients Using The Nciq And Pipsl, Bonnie A. Purtill

Dissertations, 2020-current

Unmanaged hearing loss can have profound cognitive, social, and emotional impacts on a person’s life. Cochlear implants improve functional skills such as auditory detection and speech discrimination, and have also been shown to improve quality of life. Health related quality of life (HRQoL) measures are a great tool to assess mental, physical, and social changes after cochlear implantation. While previous research has established improvement in HRQoL after cochlear implantation, there remains a lack of research evaluating long-term effects of cochlear implants for post-lingually and bilaterally deafened adults. Using a disease specific HRQoL questionnaire—Nijmegen Cochlear Implant Questionnaire (NCIQ) and a social …

Temporal Modulation Transfer Functions Of Amplitude-Modulated Cervical Vestibular Evoked Myogenic Potentials In Young Adults, Kerri Lawlor

Dissertations, 2020-current

Cervical vestibular evoked myogenic potentials (cVEMPs) are widely used to evaluate saccular function in clinical and research applications. Typically, transient tonebursts are used to elicit cVEMPs. In this study, we used bone-conducted amplitude-modulated (AM) tones to elicit AMcVEMPs. This new approach allows the examination of phase-locked vestibular responses across a range of modulation frequencies. Currently, cVEMP temporal modulation transfer functions (TMTFs) are not well defined. The purposes of the present study were 1) to characterize the AMcVEMP TMTF in young, healthy individuals, 2) to compare AMcVEMP TMTFs across different analysis approaches, and 3) to determine the upper frequency limit of …

Assessing Word Recognition Through Head Turn Preference In Infants With Chronic Otitis Media, Allison E. Schmidt

Dissertations, 2020-current

Previous studies across a variety of different languages have shown that eleven-month-olds tested via the head-turn preference paradigm show a preference for familiar words over unfamiliar words, as demonstrated by longer look times. This study examined the effect of chronic otitis media on the preference for familiar over unfamiliar words. Nine eleven-month-old children (mean age 342 days, SD = 9.61) with chronic ear infections, defined as three or more diagnoses before the test date, were tested using wordlists adapted from a study performed by Vihman et al. (2004). Children with a history of chronic otitis media did not show a …

Measuring Listening Effort Using Physiological, Behavioral And Subjective Methods In Normal Hearing Subjects: Effect Of Signal To Noise Ratio And Presentation Level, Lakshmi Magudilu Srishyla Kumar

Dissertations, 2020-current

The main objective of the study is to compare the effectiveness of pupillometry, working memory and subjective rating scale —the physiological, behavioral, and subjective measures of listening effort— at different signal to noise ratios (SNR) and presentation levels: when administered together. Eleven young normal hearing individuals with mean age of 21.7 years (SD=1.9 years) participated in the study. The HINT sentences were used for speech perception in noise task. The listening effort was quantified using peak pupil dilation, working memory, working memory difference, subjective rating of listening and recall effort. The rating of perceived performance, frustration level and …

Induction Of Nocebo Effects By Verbal Suggestions During The Caloric Test, Abbey Weist

Dissertations, 2020-current

The caloric test is the most frequently performed vestibular diagnostic test and is considered the “gold-standard” for the assessment of the peripheral vestibular system. Using a warm or cool stimulus, the caloric test alters the temperature gradient in the vestibular system resulting in nausea and dizziness. The nocebo effect is a phenomenon that can occur when negative expectations result in negative effects. No study has examined whether expectations of nausea and dizziness during the caloric test enhance the experience of unwanted symptoms. The purpose of this investigation was to determine whether a nocebo response can be elicited during the caloric …

Music And Speech Perception In Pre-Lingually Deafened Young Listeners With Cochlear Implants: A Preliminary Study Using Sung Speech, Harley J. Wheeler

Dissertations, 2020-current

Timbre and pitch cues, though definitionally and physically distinct characteristics of sound, are attributes of all sound signals. A body of literature has shown that alteration of one characteristic can influence the perception of the other; e.g., speech spoken with an atypical contour of pitch can influence a listener's accuracy in identifying the words spoken; conversely, whether a melodic contour is presented via a MIDI piano representation or as sung speech can influence the accuracy of identification of the pitches' contour. Trends for these interactions have been documented for normal hearing children and adults, as well as postlingually deafened adult …

Cervical Vestibular-Evoked Myogenic Potentials (Cvemps): "Differentiation Of Inter-Neck Emg Symmetry Between Children And Adults", Ellen Jones

Senior Honors Projects, 2010-2019

A cervical Vestibular-Evoked Myogenic Potential (cVEMP) is one of the few objective vestibular diagnostic tests available for pediatric populations. This test evaluates the functionality of the saccule end organ through an inhibitory reflex on the sternocleidomastoid (SCM) muscle that inhibits the level of electromyographic (EMG) activity (Wiener-Vacher, 2013). Because the saccule response is measured as an inhibition of EMG in the SCM, it is imperative that the SCM have a tonic contraction prior to eliciting the response and that the contraction of the SCM is equal on the right and left sides. It is generally accepted that young, healthy adults …

The Feasibility Of Standardized Cognitive Assessments For Vestibular Patients, Brynn Morales

Senior Honors Projects, 2010-2019

Vestibular dysfunction, or impairments in the inner ear and/or brain structures that process sensory information and help control balance, has a high correlation with cognitive deficits, or problems with mental processes. This relationship negatively affects daily activities and quality of life in persons that live with vestibular dysfunction. Though there is sufficient research proving the relationship, few studies have applied that information in ways to better help the population with vestibular dysfunction. The purpose of this study was to assess the feasibility of a cognitive assessment battery (a set of correlated assessments delivered in one session) tailored to measuring performance …

The Test-Retest Reliability Of Binaural-Processing Tasks At Home Versus A Clinical Environment, Logan Grace Faust

Dissertations, 2014-2019

Objective: Investigate the reliability of a custom-designed, portable, stereo-hearing testing system (as in the Ganev, 2017, Au.D. dissertation) when subjects self-administer two different stereo-hearing tasks at home. Results obtained under known and supervised conditions at a university clinic or lab versus unknown conditions at the participants’ homes were compared. Intra-subject comparison, and inter-subject trends, discerned the reliability of patient setup and self-administration of the two tasks.
Design: Ten subjects were evenly split among two conditions: five subjects each setup and self-administered the tasks first at home and then received direction in the clinic, and five received direction and did the …

Music And Speech Perception In Children Using Sung Speech: Effects Of Neurocognitive Factors, Victoria A. André

Dissertations, 2014-2019

The current study aimed to explore normal-hearing children's ability to utilize pitch and timbre cues and how these findings correlate with neurocognitive factors. Participants were recruited if they had English as their first language and no formal musical training or 3+ years of formal musical training. Twenty normal-hearing children, age 7.5-14.5 years (mean = 10.5; n=20) were recruited for the study. Nonverbal intelligence, receptive vocabulary, and auditory working memory were assessed using subtests of the Kaufman Brief Intelligence Test-2, Peabody Picture Vocabulary Test-4, and Comprehensive Test of Phonological Processing-2, respectively. Raw scores were used to analyze these neurocognitive abilities in …

Auditory And Somatosensory Pre-Pulse Inhibition In Mice, Anna Louthan

Dissertations, 2014-2019

Both hearing and somatosensation are sensory responses to vibrations, and here we show a way to investigate such mechanoreceptive psychophysics alone and in combination. Pre-pulse inhibition (PPI) is a well-known, unconditioned, and reflexive technique for measuring sensory thresholds with a wide variety of stimuli and laboratory animals. In this paper, we explore interactions between auditory and somatosensory PPI in normal mice. Fifteen C57/BL6J mice were tested three times each. Ages varied between one and six months. Testing followed published procedures from our lab and others, except the pre-pulses were auditory, somatosensory (vibration of the test chamber), or both. The auditory …

Comparing Two Naturalistic Pragmatic Assessments: The Celf-5 Pragmatic Activities And The Yale In Vivo Pragmatic Protocol (Yipp), Rebecca Reid

Senior Honors Projects, 2010-2019

Pragmatics, or the social use of language, is a dimension of communication skills that is very difficult to assess due to its dependence on cultural norms, situational context, and speaker differences. Of the current methods for evaluating pragmatic language skills in children, the literature most frequently recommends naturalistic assessment because it allows the clinician to most closely simulate a real-life interaction. Despite these recommendations, limited information exists to guide clinicians in making decisions about which activities yield the most representative pragmatic language sample. This preliminary study compared two naturalistic pragmatic assessments, the Pragmatic Activities from the Clinical Evaluation of Language …

Does Emg Monitoring In A Cvemp Matter?, Kimberly Fleck

Senior Honors Projects, 2010-2019

To determine if EMG monitoring or the use of amplitude normalization would significantly reduce the amplitude variability and amplitude asymmetry of the cVEMP in children ages 3 and under, we first needed to create a control group with young, healthy adults to compare the pediatric group to. We also wanted to replicate earlier studies that showed EMG monitoring and amplitude normalization does not have an impact on the VEMP in young, healthy adults. We tested two different positions, sitting and supine. Supine is the optimal position to generate EMG, but we wanted to have control data in case the pediatric …

Melodic Contour Identification And Speech Recognition By School-Aged Children, Michael P. Morikawa

Dissertations, 2014-2019

Using the Sung Speech Corpus (SSC), which encompasses a single database that contains musical pitch, timbre variations and speech information in identification tasks, the current study aimed to explore the development of normal-hearing children’s ability to use the pitch and timbre cues. Thirteen normal hearing children were recruited for the study ages ranging from 7 to 16 years old. Participants were separated into two separate groups: Younger (7-9) and Older (10-16). Musical Experience was taken into account as well. The Angel Sound ™ program was utilized for testing which was adopted from previous studies, most recently Crew, Galvin, and Fu …

Objective Differences Between Premium And Mid-Level Digital Hearing Aids, Chelsea C. Barry

Dissertations, 2014-2019

This ongoing study compared premium and mid-level hearing aids from major manufacturers on noise reduction and general electroacoustic characteristics. The findings of this study will contribute to the scarce independent literature evaluating currently available hearing aid technology. Measuring the overall gain reduction in response to a steady state noise can objectively test noise reduction. However, such a method does not specifically test a hearing aid’s ability to reduce speech in specific narrow frequency bands. Hanline & Rout (2008) developed a set of stimuli to evaluate multichannel noise reduction algorithms more precisely. We used these stimuli to test noise reduction abilities …

The Effects Of Age On The Perception Of Frequency In Noise, Mary E. Scherer

Dissertations, 2014-2019

Difficulty understanding speech in the presence of background noise is one of the most common complaints of older adults, both with and without hearing loss. One possible contributing factor is an age-related decline in neural synchrony (e.g., phase locking). Tones-in-noise were used in an attempt to disrupt rate-place coding of frequency and to encourage participants to use phase-locked, temporal representations of frequency during a behavioral frequency discrimination task. Fourteen adults participated in the study (five younger, aged 21-29; four middle aged, 41-50; and five older, aged 61-80). Participants had clinically normal hearing sensitivity (≤ 25 dB HL at octave frequencies …

Development And Deployment Of A Small Stereo-Hearing Testing System: Two Manuscripts, Sofia A. Ganev

Dissertations, 2014-2019

MANUSCRIPT #1 TITLE

Development of a Deployable Stereo-Hearing System

ABSTRACT

Objective: To investigate the effectiveness and efficiency of a portable stereo-hearing testing system with the intent of deployment for data collection in future studies. We quantify sound localization accuracy and speech-in-noise thresholds comparing unilateral (such as single-sided deafness) and bilateral subjects. We desired to design a small, inexpensive system that would show a large effect size between binaural and monaural subjects in a variety of stereo hearing tasks.

Methods: Subjects were tested on localization accuracy and speech understanding in noise using a laboratory-made stereo-hearing testing device. For the …

Reflection: Effect Of Age On Auditory Brainstem Responses In Mice With Epha4 Mutations, Erica L. Hoogerland

Senior Honors Projects, 2010-2019

Presbycusis, or age-related hearing loss is a condition that affects approximately 40% of the population over 65 years of age (Gates & Mills, 2005). Studying the effects of EphA4 mutations (wild type, heterozygous, and homozygous) mice is fundamental in understanding the relationship between onset of age-related hearing loss, in both the mammalian population and the human population. In order to further understanding of age-related hearing loss, the researchers evaluated thirty-six mice in a preliminary study from two months to nine months of age. Following data analysis, the researchers confirmed the results by continuing a second round of testing. The hearing …

Build-Up Effect Of Auditory Stream Segregation Using Amplitude-Modulated Narrowband Noise, Harley J. Wheeler

Senior Honors Projects, 2010-2019

Recent psychoacoustic experiments (Böckmann-Barthel et al., 2014; Deike et al., 2012) have re-examined research regarding stream segregation and the build-up effect. Stream segregation is the ability to discern auditory objects within a stream of information, such as distinguishing one voice amongst background noise or an instrument within an orchestra. Initial works examining this topic proposed that auditory information is not immediately distinguished as various streams, but rather that differences accumulate over time, allowing listeners to segregate information following a period of build-up (i.e., the build-up effect); whereas more current findings indicate a build-up period is unnecessary for segregation. This experiment’s …

Release From Masking: Behavioral And Physiological Masking Level Differences, Sarah L. Hodgson

Dissertations, 2014-2019

Binaural hearing offers several advantages over monaural hearing and is believed to be one factor that is involved in the ability to understand speech in background noise. Binaural hearing involves analysis of interaural timing and intensity differences in signals arriving at the two ears which provides listeners with sound localization cues as well as signal in noise detection. When sounds arrive at each ear at slightly different times, there may be a release from the effects of background noise, allowing listeners to detect softer sounds in noise. Masking Level Differences (MLDs) have been widely used to evaluate behavioral binaural processing. …

Variability In Clinically Measured Wideband Acoustic Immittance Over Time In Young And Old Adults, Allison G. Mcgrath

Dissertations, 2014-2019

Wideband acoustic immittance (WAI) measures of the middle ear have the potential to increase our ability to detect changes in the middle ear transfer function not seen using traditional tympanometry. In order to use this new tool diagnostically we must first understand its normal clinical variability. The present study aimed to investigate the variability that occurs when wideband acoustic immittance (WAI) is measured clinically within subjects as a function of subject age, as a function of time, and as a function of pressure. A total of thirty-six ears from eighteen subjects were studied (n=18 young adults ears, n=18 older adult …

Pre-Pulse Inhibition Assessment Of Sound Localization In Mice, Kathryn C. Brooks

Senior Honors Projects, 2010-2019

The purpose of my Honors Research Project was to assist Dr. Megan

Klingenberg in completing part of the research in her final dissertation project. Dr.

Klingenberg’s project was based off of a study done by Allen and Ison in 2010.

This study tested the auditory spatial acuity of mice using pre-pulse inhibition of

the startle reflex as the response for detecting the sound stimulus. The goal of

Dr. Klingenberg’s AuD project was “to explore the methodological, functional, and

genetic influences on sound localization using pre-pulse inhibition of the acoustic

startle response in mice”. Dr. Klingenberg’s project was broken into three …

Examining Monaural And Binaural Measures Of Phase-Locking As A Function Of Age, Larissa M. Heckler

Dissertations, 2014-2019

Understanding speech in the presence of background noise is a common complaint of middle-aged and older listeners with clinically normal audiograms. There is great interest in understanding how age-related changes in auditory physiology make it harder for older adults to understand speech in difficult listening situations, compared to young listeners. It was recently reported that middle-aged and older normal-hearing listeners showed frequency-dependent, age-related declines in the behavioral and physiological detection of interaural phase differences (Grose & Mamo, 2010; Ross et al, 2007). There is also evidence of an age-related, frequency-dependent decline in the frequency-following response (FFR) (Clinard et al., 2010), …

Pre-Pulse Inhibition Assessment Of Sound Localization In Mice: Methodological, Functional, And Genetic Considerations, Megan Klingenberg

Dissertations, 2014-2019

Sound localization is an important aspect of normal hearing. The Eph/ephin family of signaling proteins, studied here, is known to guide the formation of central auditory connections in early development, particularly topographic inputs from the lateral superior olive (LSO) to the inferior colliculus (IC). Processing in the LSO and its influences on the IC are known to be heavily involved in sound localization tasks. One way to study sound localization in mice is through pre-pulse inhibition (PPI). PPI is the phenomenon by which a weak prestimulus inhibits the response to a subsequent startle stimulus. In studying sound localization, the prestimulus …

Binaural Listening In Young And Middle-Aged Adults: Interaural Phase Differences And Speech-In-Noise Measures, Caitlin Cotter

Dissertations, 2014-2019

Difficulty understanding speech in the presence of noise is a common complaint of middle-aged and older adults with and without hearing loss. There is an incomplete picture of what contributes to difficulties understanding speech-in-noise in adults who have normal audiograms. As humans we listen binaurally, so declines in binaural processing may contribute to speech-in-noise difficulties. We examined the effects of age on the upper frequency limit of interaural phase difference (IPD) detection and IPD detection at fixed frequencies. We also examined a speech-in-noise measure of spatial separation across young and middle-aged, normal-hearing individuals.

Participants were young (n=12) and middle-aged (n=8) …

Effects Of Training And Lung Volume Levels On Voice Onset Control And Cortical Activation In Singers, Nicholas A. Barone

Dissertations, 2014-2019

Singers need to counteract respiratory elastic recoil at high and low lung volume levels (LVLs) to maintain consistent airflow and pressure while singing. Professionally trained singers modify their vocal and respiratory systems creating a physiologically stable and perceptually pleasing voice quality at varying LVLs. In manuscript 1, we compared non-singers and singers on the initiation of a voiceless plosive followed by a vowel at low (30% vital capacity, VC), intermediate (50%VC), and high (80%VC) LVLs. In manuscript 2, we examined how vocal students (singers in manuscript 1) learn to control their voice onset at varying LVLs before and after a …