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2017

Aged; Cognition -- drug effects; Dementia -- etiology; Proton Pump Inhibitors -- adverse effects; Vitamin B 12 Deficiency -- complications

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Association Between Proton Pump Inhibitor Use & Dementia: A Two-Fold Approach, Lisa Steers Jan 2017

Association Between Proton Pump Inhibitor Use & Dementia: A Two-Fold Approach, Lisa Steers

Physician Assistant Scholarly Project Posters

An observational study of data derived from the German Study on Aging, Cognition and Dementia indicated that proton pump inhibitor use was associated with dementia risk (Benmassaoud, McDonald, & Lee, 2016). The purpose of this study is to explore a two-fold approach between proton pump inhibitor use and dementia. This two-fold approach will first investigate the association between dementia and proton pump inhibitor use and secondly, the proposed pathophysiology behind it. This approach to proton pump inhibitor use and dementia will allow for providers to utilize the association and make decisions to avoid chronic proton pump inhibitor use in effort …